Cofilin-1 (1-166, His-tag) - AR09012PU-N

Product Description for Cofilin-1

Cofilin-1.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	0.1 mg
Synonyms	18 kDa phosphoprotein, CFL, CFL1, Cofilin non-muscle isoform, p18
Presentation	Purified
Molecular weight	20 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: P23528
Purity	> 95 % >/= 95% by SDS PAGE
Add. information	NCBI Accession : NP _005498
Background	Cofilin is a family of actin-binding proteins which disassembles actin filaments. It is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.
Concentration	1.0 mg/ml
General Readings	Mannherz H.G, et al , (2007). J. Mol. Biol. 366 (3) 745-755. Olsen J.V., et al , (2006). Cell. 127 (3), 635-648.
Storage	Store (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Source	E. coli
Description	Description: Recombinant human Cofilin, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. AA Sequence: `MGSSHHHHHH SSGLVPRGSH MASGVAVSDG VIKVFNDMKV RKSSTPEEVK KRKKAVLFCL SEDKKNIILE EGKEILVGDV GQTVDDPYAT FVKMLPDKDC RYALYDATYE TKESKKEDLV FIFWAPESAP LKSKMIYASS KDAIKKKLTG IKHELQANCY EEVKDRCTLA EKLGGSAVIS LEGKPL` Molecular weight: 20 kDa (186 aa)
Format	Buffer System: 20 mM Tris pH 8.0, 10 % Glycerol Purity: >95% >/= 95% by SDS PAGE State: Liquid purified protein Purified