Product Description for CD26 / DPP4
CD26 / DPP4.
Presentation: Purified
Presentation: Purified
Properties for CD26 / DPP4
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 100 µg |
| Synonyms | ADABP, ADCP2, Adenosine deaminase complexing protein 2, DPP IV, Dipeptidyl peptidase 4, Dipeptidyl peptidase IV, T-cell activation antigen CD26, TP103 |
| Presentation | Purified |
| Molecular weight | 86.4 kDa |
| Source | High-5 Insect cells |
| Specactivity | > 50 unit/mg |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Purity | > 95 % by SDS PAGE |
| Background | DPP4, dipeptidyl peptidase-4 is a complex enzyme expressed on the surface of most cell types and is a serine exopeptidase that cleaves x-proline dipeptides from the N-terminus of polypeptides. DPP4 protein is associated with intracellular signal transduction, apoptosis and plays an important role in tumor biology. There are at least 63 substrates which can bind specifically to DPP4 enzyme including growth factors, chemokines, neuro peptides. Furthermore, DPP4 plays a major role in glucose metabolism by cleaving incretins such as glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1). |
| Concentration | 0.5 mg/ml |
| General Readings | Pratley RE and Salsali A. (2007) Curr Med Res Opin. 23(4):919-31. Rosenstock J. and Zinman B. (2007) Curr Opin Endocrino Diabetes Obes.60(11):1454-70. Barnett A. (2006). J.Clin. Pract. 60(11):1454-70. |
| Storage | Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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