Product Description for RAD1
RAD1.
Presentation: Purified
Presentation: Purified
Properties for RAD1
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.25 mg |
| Synonyms | Cell cycle checkpoint protein RAD1, DNA repair exonuclease rad1 homolog, REC1, Rad1-like DNA damage checkpoint protein |
| Presentation | Purified |
| Molecular weight | 33.9 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Purity | > 90 % by SDS - PAGE |
| Background | RAD1 is a component of a heterotrimeric cell cycle checkpoint complex, known as the 9-1-1 complex, that is activated to stop cell cycle progression in response to DNA damage or incomplete DNA replication. This complex also contains the Rad9 and Hus1 proteins and is believed to be involved in cellular responses to DNA damage, possibly by associating with Rad17 and several components of the PCNA-loading heteropentamer, replication factor C |
| Concentration | 0.5 mg/ml (determined by Bradford assay) |
| General Readings | Liu Y., et al. (2010) J Biol Chem. 285(8):5974-82. Yazinski SA., et al. (2009) Proc Natl Acad Sci U S A. 106(50):21282-7. |
| Storage | Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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