Product Description for RND3 / ARHE
RND3 / ARHE.
Presentation: Purified
Presentation: Purified
Properties for RND3 / ARHE
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.1 mg |
| Synonyms | MemB protein, RHO8, RHOE, Rho family GTPase 3, Rho-related GTP-binding protein RhoE |
| Presentation | Purified |
| Molecular weight | 29.2 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
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|---|---|
| Purity | > 90 % by SDS - PAGE |
| Background | Rho-related GTP-binding protein RhoE, also known as RND3, is a small GTPase of the Ras superfamily that regulate the organization of the actin cytoskeleton in response to extracellular growth factors. RND3 activity leads to a decrease in stress fibers and increased cell migration, at least in part through regulation of the Rho-dependent kinase ROCK1. Also, RND3 has been implicated in inhibition of DNA-damage induced apoptosis and cell cycle arrest. |
| Concentration | 0.5 mg/ml (determined by Bradford assay) |
| General Readings | Riento K., et al. (2005) Mol Cell Biol. 23:4219-29. Boswell S A., et al. (2007) J Biol Chem. 282:4850-8. |
| Storage | Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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