Product Description for Fascin
Fascin.
Presentation: Purified
Presentation: Purified
Properties for Fascin
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.1 mg |
| Synonyms | 55 kDa actin-bundling protein, Dendritic cell marker, FAN1, HSN, SCN1, SNL, Singed-like protein, p55 |
| Presentation | Purified |
| Molecular weight | 56.7 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Purity | > 95 % by SDS - PAGE |
| Background | FSCN1 is an actin-bundling protein that provides rigidity to filopodial bundles to efficiently push the membrane forward during cytoskeleton remodeling and cell migration. Probably involved in the assembly of actin filament bundles present in microspikes, membrane ruffles, and stress fibers. And this protein is absent from most normal epithelia yet is upregulated in multiple forms of human carcinoma, where its expression correlates clinically with a poor prognosis. FSCN1 expression has been localized to neurons, glial cells, and endothelial cells. |
| Concentration | 1.0 mg/ml (determined by Bradford assay) |
| General Readings | Wu D, et al. (2010) Ann Oncol. 21(3):589-96. Shin H, et al. (2009) Phys Rev Left 103(23):238102. |
| Storage | Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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