Product Description for OGG1
OGG1.
Presentation: Purified
Presentation: Purified
Properties for OGG1
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.5 mg |
| Synonyms | MMH, MUTM, N-glycosylase/DNA lyase, OGH1 |
| Presentation | Purified |
| Molecular weight | 41.2 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Purity | > 90 % by SDS-PAGE |
| Background | OGG1, also known as 8-oxoguanine glycosylase, is a DNA glycosylase enzyme involved in base excision repair. This protein is the primary enzyme responsible for the excision of 7,8-dihydro-8-oxoguanine (8-oxoG), a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen species (ROS). It has a beta lyase activity that nicks DNA 3' to the lesion. |
| Concentration | 0.5 mg/ml (determined by Bradford assay) |
| General Readings | Seeberg E., et al. (2002). Nucleic Acids Res. 30(11):2349-57. Hodges NJ., et al (2010). DNA Repair (Amst). 9(2):144-52. |
| Storage | Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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