Product Description for BIN1 / AMPHL
BIN1 / AMPHL.
Presentation: Purified
Presentation: Purified
Properties for BIN1 / AMPHL
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.1 mg |
| Synonyms | Amphiphysin II, Amphiphysin-like protein, Box-dependent myc-interacting protein 1, Bridging integrator 1, Myc box-dependent-interacting protein 1 |
| Presentation | Purified |
| Molecular weight | 50.4 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Purity | > 90 % by SDS – PAGE |
| Background | BIN1 is a nucleocytoplasmic adaptor protein, one of which was initially identified as MYC-interacting protein with features of a tumor suppressor. This protein interacts with and inhibits the oncogenic activity of the myc oncoprotein that has a major role in many human cancers. The loss of Bin1 may contribute to growth deregulation in cancer cells in carcinoma of the breast, colon, lung, cervix, prostate and liver. |
| Concentration | 1.0 mg/ml (determined by Bradford assay) |
| General Readings | Nanda SK., et al. (2006) Gastroenterology. 130(3):794-809. |
| Storage | Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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