MMAB (33-250, His-tag) - AR09615PU-N

Product Description for MMAB

MMAB.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	0.1 mg
Synonyms	Cob(I)alamin adenosyltransferase, Cob(I)yrinic acid a, Methylmalonic aciduria type B, c-diamide adenosyltransferase
Presentation	Purified
Molecular weight	26.3 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: Q96EY8
Purity	> 95 % by SDS - PAGE
Background	MMAB is a protein that catalyzes the final step in the conversion of vitamin B(12) into adenosylcobalamin (AdoCbl), a vitamin B12 containing coenzyme for methylmalonyl-CoA mutase(MCM). Impaired MMAB activity leads to the inherited disorder vitamin B12 dependent methylmalonic aciduria linked to the cblB complementation group.
Concentration	1.0 mg/ml (determined by Bradford assay)
General Readings	Gravel RA., et al. (2009) Mol Genet Metab. 98(3):278-84. Edwards AM., et al (2004) J Biol Chem. 279(22):23646-53.
Storage	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human MMAB protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. AA Sequence: `MGSSHHHHHH SSGLVPRGSH MQSRGPQGVE DGDRPQPSSK TPRIPKIYTK TGDKGFSSTF TGERRPKDDQ VFEAVGTTDE LSSAIGFALE LVTEKGHTFA EELQKIQCTL QDVGSALATP CSSAREAHLK YTTFKAGPIL ELEQWIDKYT SQLPPLTAFI LPSGGKISSA LHFCRAVCRR AERRVVPLVQ MGETDANVAK FLNRLSDYLF TLARYAAMKE GNQEKIYKKN DPSAESEGL` Molecular weight: (239aa), confirmed by MALDI-TOF
Format	Buffer System: 20 mM Tris-HCl Buffer (pH 7.5) containing 10% Glycerol Purity: >95% by SDS - PAGE State: Liquid purified protein Purified