Product Description for TXNDC4 / ERP44
TXNDC4 / ERP44.
Presentation: Purified
Presentation: Purified
Properties for TXNDC4 / ERP44
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.5 mg |
| Synonyms | Endoplasmic reticulum resident protein ERp44, KIAA0573, Thioredoxin domain-containing protein 4 |
| Presentation | Purified |
| Molecular weight | kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Purity | > 90 % by SDS - PAGE |
| Background | ERP44 is a novel endoplasmic reticulum chaperone involved in thiol-dependent retention of the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. The protein inhibits the calcium channel activity of ITPR1. This protein may have a role in the control of oxidative protein folding in the endoplasmic reticulum. |
| Concentration | 1.0 mg/ml (determined by Bradford assay) |
| General Readings | von Figura K., et al. (2008) J Biol Chem. 283(10):6375-83. Sitia R., et al. (2002) EMBO J. 21(4):835-44. |
| Storage | Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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