Product Description for Annexin A8 / ANXA8
Annexin A8 / ANXA8.
Presentation: Purified
Presentation: Purified
Properties for Annexin A8 / ANXA8
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.5 mg |
| Synonyms | ANX8, Annexin VIII, Annexin-8, VAC-beta, Vascular anticoagulant-beta |
| Presentation | Purified |
| Molecular weight | kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Purity | > 90 % by SDS - PAGE |
| Background | ANXA8, also known as Annexin A8, a member of the annexin family of evolutionarily conserved Ca2+ and phospholipid binding proteins. This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. Where co-expressed in the same tissues, ANXA8 is often expressed at a 100-fold lower level than Annexin A5. However, ANXA8 is preferentially expressed in acute promyelocytic leukemia (APL) cells which may relate to its role in hematopoietic cell differentiation. |
| Concentration | 1.0 mg/ml (determined by Bradford assay) |
| General Readings | Movitz C., et al. (2010) J Biol Chem. 285(19):14338-45. Torosyan Y., et al. (2010) Oncogene. 29(17):2457-66. |
| Storage | Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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