AR09636PU-N RCL (1-174, His-tag)

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0.1 mg / €320.00
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RCL

AR09636PU-N

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  • AR09636PU-N

Product Description for RCL

RCL.
Presentation: Purified

Properties for RCL

Product Category Proteins & Growth Factors
Quantity 0.1 mg
Synonyms C6orf108, Deoxyribonucleoside 5'-monophosphate N-glycosidase, c-Myc-responsive protein Rcl
Presentation Purified
Molecular weight 21.2 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
O43598
Purity > 95 % by SDS - PAGE
Background Deoxyribonucleoside 5'-monophosphate N-glycosidase isoform 1, also known as RCL, belonged to the N-deoxyribosyltransferase family. This protein catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base. RCL was identified on the basis of its stimulation by c-Myc protein. The latter is a transcription factor that participates in the regulation of cell proliferation, differentiation, and apoptosis.
Concentration 1.0 mg/ml (determined by Bradford assay)
General Readings Ghiorghi Y K., et al. (2007) J Biol Chem. 282(11):8150-6.
Munqall A J., et al. (2003) Nature. 425(6960):805-11.
Storage Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human RCL protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MAAAMVPGRS ESWERGEPGR PALYFCGSIR GGREDRTLYE RIVSRLRRFG TVLTEHVAAA ELGARGEEAA GGDRLIHEQD LEWLQQADVV VAEVTQPSLG VGYELGRAVA FNKRILCLFR PQSGRVLSAM IRGAADGSRF QVWDYEEGEV EALLDRYFEA DPPGQVAASP DPTT
Molecular weight:
(194aa), confirmed by MALDI-TOF
Format
Buffer System:
In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol
Purity:
>95% by SDS - PAGE
State:
Liquid purified protein
Purified
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