AR09660PU-N Secretagogin (SCGN) (1-276, His-tag)

Search for all "Secretagogin (SCGN)"

50 µg / €320.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

Secretagogin (SCGN)

AR09660PU-N

More Views

  • AR09660PU-N

Product Description for Secretagogin (SCGN)

Secretagogin (SCGN).
Presentation: Purified

Properties for Secretagogin (SCGN)

Product Category Proteins & Growth Factors
Quantity 50 µg
Synonyms CALBL, EF-hand calcium binding protein, SECRET, SEGN, Setagin
Presentation Purified
Molecular weight 34.2 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
O76038
Purity > 90 % by SDS–PAGE
Background SCGN, also known as secretagogin, is a cytoplasmic protein that contains six EF-hand domains and is related to the calicium-binding proteins Calretinin and Calbindin D28K. This protein is thought to be involved in cell proliferation and KCl (potassium chloride)-mediated calcium flux events. Through its interaction with KCl and its subsequent ability to modulate calcium storage pools within the cell, SCGN may function to negatively control growth and differentiation rates and, thus, indirectly inhibit cell replication.
Concentration 1.0 mg/ml (determined by Bradford assay)
General Readings
  1. Wagner L., et al. (2000) J Biol Chem. 275(32):24740-51.
  2. Gartner W., et al. (2001) Cereb Cortex. 11(12):1161-9.
Storage Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant SCGN protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MDSSREPTLG RLDAAGFWQV WQRFDADEKG YIEEKELDAF FLHMLMKLGT DDTVMKANLH KVKQQFMTTQ DASKDGRIRM KELAGMFLSE DENFLLLFRR ENPLDSSVEF MQIWRKYDAD SSGFISAAEL RNFLRDLFLH HKKAISEAKL EEYTGTMMKI FDRNKDGRLD LNDLARILAL QENFLLQFKM DACSTEERKR DFEKIFAYYD VSKTGALEGP EVDGFVKDMM ELVQPSISGV DLDKFREILL RHCDVNKDGK IQKSELALCL GLKINP
Molecular weight:
(296aa), confirmed by MALDI-TOF
Format
Buffer System:
20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol, 1mM DTT, 0.1M NaCl
Purity:
>90% by SDS–PAGE
State:
Liquid purified protein
Purified
  • LinkedIn