AR09670PU-L Thymidine phosphorylase (TYMP) (11-482, His-tag)

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0.5 mg / €1,070.00
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Thymidine phosphorylase (TYMP)

AR09670PU-L

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  • AR09670PU-L

Product Description for Thymidine phosphorylase (TYMP)

Thymidine phosphorylase (TYMP).
Presentation: Purified

Properties for Thymidine phosphorylase (TYMP)

Product Category Proteins & Growth Factors
Quantity 0.5 mg
Synonyms ECGF1, Gliostatin, PD-ECGF, Platelet-derived endothelial cell growth factor, TdRPase
Presentation Purified
Molecular weight 51.3 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P19971
Purity > 90 % by SDS - PAGE
Background Thymidine phosphorylase precursor, also known TYMP, is a platelet-derived endothelial cell growth factor that catalyzes the formation of thymine and 2-deoxy-D-ribose-1-phosphate from thymidine and orthophosphate. It is an angiogenic inducer that potently stimulates the growth of endothelial cells and induces chemotaxis. Increased expression of TYMP is seen in a wide variety of different solid tumors and inflammatory diseases and is often associated with poor prognosis.
Concentration 1.0 mg/ml (determined by Bradford assay)
Storage Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human TYMP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MAPPAPGDFS GEGSQGLPDP SPEPKQLPEL IRMKRDGGRL SEADIRGFVA AVVNGSAQGA QIGAMLMAIR LRGMDLEETS VLTQALAQSG QQLEWPEAWR QQLVDKHSTG GVGDKVSLVL APALAACGCK VPMISGRGLG HTGGTLDKLE SIPGFNVIQS PEQMQVLLDQ AGCCIVGQSE QLVPADGILY AARDVTATVD SLPLITASIL SKKLVEGLSA LVVDVKFGGA AVFPNQEQAR ELAKTLVGVG ASLGLRVAAA LTAMDKPLGR CVGHALEVEE ALLCMDGAGP PDLRDLVTTL GGALLWLSGH AGTQAQGAAR VAAALDDGSA LGRFERMLAA QGVDPGLARA LCSGSPAERR QLLPRAREQE ELLAPADGTV ELVRALPLAL VLHELGAGRS RAGEPLRLGV GAELLVDVGQ RLRRGTPWLR VHRDGPALSG PQSRALQEAL VLSDRAPFAA PSPFAELVLP PQQ
Molecular weight:
(493aa), confirmed by MALDI-TOF
Format
Buffer System:
20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol
Purity:
>90% by SDS - PAGE
State:
Liquid purified protein
Purified
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