SUMO3 / SMT3A (1-92, His-tag) - AR09688PU-L

Product Description for SUMO3 / SMT3A

SUMO3 / SMT3A.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	0.5 mg
Synonyms	SMT3 homolog 1, SMT3H1, SUMO-3, Small ubiquitin-related modifier 3, Ubiquitin-like protein SMT3A
Presentation	Purified
Molecular weight	12.6 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: P55854
Purity	> 95 %
Background	SUMO3, also known as small ubiquitin-related modifier 3, is a member of the SUMO protein family and functions in a manner similar to ubiquitin. However, unlike ubiquitin which targets proteins for degradation, SUMO3 protein participates in a number of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It regulates amyloid beta generation and may be critical in the onset or progression of Alzheimer’s disease.
Concentration	1.0 mg/ml (determined by Bradford assay)
General Readings	Evdokimov E., et al. (2008), J Cell Sci, 121:4106-13. Tatham MH., et al. (2001). J Biol Chem. 276:35368-74.
Storage	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human SUMO3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. AA Sequence: `MGSSHHHHHH SSGLVPRGSH MSEEKPKEGV KTENDHINLK VAGQDGSVVQ FKIKRHTPLS KLMKAYCERQ GLSMRQIRFR FDGQPINETD TPAQLEMEDE DTIDVFQQQT GG` Molecular weight: (112aa) confirmed by MALDI-TOF (molecular size on SDS-PAGE will appear higher).
Format	Buffer System: 20mM Tris-HCl buffer (pH8.0) containing 20% glycero, 0.1M NaCl, 1mM DTT Purity: >95% State: Liquid purified protein Purified