AR09710PU-L Annexin A11 / ANXA11 (1-505, His-tag)

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0.5 mg / €1,070.00
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Annexin A11 / ANXA11

AR09710PU-L

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  • AR09710PU-L

Product Description for Annexin A11 / ANXA11

Annexin A11 / ANXA11.
Presentation: Purified

Properties for Annexin A11 / ANXA11

Product Category Proteins & Growth Factors
Quantity 0.5 mg
Synonyms 56 kDa autoantigen, ANX11, Annexin XI, Annexin-11, CAP-50, Calcyclin-associated annexin 50
Presentation Purified
Molecular weight 56.6 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P50995
Purity > 95 %
Background ANXA11 (Annexin A11) is a member of the annexin family, a group of calcium-dependent phospholipid-binding proteins. Annexins have unique N-terminal domains and conserved C-terminal domains, which contain the calcium-dependent phospholipid-binding sites. ANXA11 binds specifically to calcyclin in a calcium-dependent manner. And it required for midbody formation and completion of the terminal phase of cytokinesis. This protein is a 56-kD antigen recognized by sera from patients with various autoimmune diseases.
Concentration 0.25 mg/ml (determined by Bradford assay)
General Readings Tomas A., et al. (2004) J. Cell Biol. 165:813-822.
Satoh., et al. (2002) Biochem. Biophys. Res. Commun. 291 (5): 1166–72.
Storage Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant ANXA11 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MSYPGYPPPP GGYPPAAPGG GPWGGAAYPP PPSMPPIGLD NVATYAGQFN QDYLSGMAAN MSGTFGGANM PNLYPGAPGA GYPPVPPGGF GQPPSAQQPV PPYGMYPPPG GNPPSRMPSY PPYPGAPVPG QPMPPPGQQP PGAYPGQPPV TYPGQPPVPL PGQQQPVPSY PGYPGSGTVT PAVPPTQFGS RGTITDAPGF DPLRDAEVLR KAMKGFGTDE QAIIDCLGSR SNKQRQQILL SFKTAYGKDL IKDLKSELSG NFEKTILALM KTPVLFDIYE IKEAIKGVGT DEACLIEILA SRSNEHIREL NRAYKAEFKK TLEEAIRSDT SGHFQRLLIS LSQGNRDEST NVDMSLAQRD AQELYAAGEN RLGTDESKFN AVLCSRSRAH LVAVFNEYQR MTGRDIEKSI CREMSGDLEE GMLAVVKCLK NTPAFFAERL NKAMRGAGTK DRTLIRIMVS RSETDLLDIR SEYKRMYGKS LYHDISGDTS GDYRKILLKI CGGND
Molecular weight:
(525aa) confirmed by MALDI-TOF
Format
Buffer System:
PBS containing 20% glycerol, 2mM DTT, 100mM NaCl
Purity:
>95%
State:
Liquid purified protein
Purified
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