Parvalbumin alpha / PVALB (1-110, His-tag) - AR09718PU-L

Product Description for Parvalbumin alpha / PVALB

Parvalbumin alpha / PVALB.
Presentation: Purified

Immunogen	Swiss Prot Num: P20472
Purity	> 95 %
Background	Parvalbumin alpha, also known PVALB, belongs to a larger group of EF hand proteins. It is a high affinity calcium ion-binding protein that is structurally and functionally similar to calmodulin and troponin C. Parvalbumin is expressed in a specific population of GABAergic interneurones which are thought to play a role in maintaining the balance between excitation and inhibition in the cortex as well as the hippocampus.
Concentration	1.0 mg/ml (determined by Bradford assay)
General Readings	Klausberqer T., et al. (2005) J Neurosci. 25(42):9782-93.
Storage	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human PVALB protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. AA Sequence: `MGSSHHHHHH SSGLVPRGSH MGSHMSMTDL LNAEDIKKAV GAFSATDSFD HKKFFQMVGLKKKSADDVKK VFHMLDKDKS GFIEEDELGF ILKGFSPDAR DLSAKETKML MAAGDKDGDG KIGVDEFSTL VAES` Molecular weight: (134aa) confirmed by MALDI-TOF
Format	Buffer System: 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 50mM NaCl Purity: >95% State: Liquid purified protein Purified