Product Description for TNIP1
TNIP1.
Presentation: Purified
Presentation: Purified
Properties for TNIP1
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 50 µg |
| Synonyms | HIV-1 Nef-interacting protein, KIAA0113, NAF1, Nef-associated factor 1, Nip40-1, TNFAIP3-interacting protein 1, VAN, Virion-associated nuclear shuttling protein |
| Presentation | Purified |
| Molecular weight | 51.8 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
|
|---|---|
| Purity | > 75 % |
| Background | TNIP1 (TNFAIP3-interacting protein 1) has been shown to interacts with zinc finger protein A20/TNFAIP3 and inhibits TNF-induced NF-kappa-B-dependent gene expression by interfering with an RIP- or TRAF2-mediated transactivation signal. In addition, interacts with HIV-1 matrix protein and is packaged into virions and overexpression can inhibit viral replication. It may regulate matrix nuclear localization, both nuclear import of PIC (Preintegration complex) and export of GAG polyprotein and viral genomic RNA during virion production. |
| Concentration | 0.25 mg/ml (determined by Bradford assay) |
| General Readings | He CF., et al. (2010) Lupus 19(10):1181-6. Gateva V., et al. (2009) Nat Genet.41(11):1228-33. |
| Storage | Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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