Product Description for NP
NP.
Presentation: Purified
Presentation: Purified
Properties for NP
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.1 mg |
| Synonyms | Inosine Phosphorylase, PNP, PNP1, Purine Nucleoside Phosphorylase |
| Presentation | Purified |
| Molecular weight | 43.2 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
|
|---|---|
| Purity | > 90 % |
| Background | PNP belongs to the PNP/MTAP phosphorylase family of proteins. This protein catalyzes the reversible phosphorolysis of ribonucleosides and 2’-deoxyribonucleosides with specificity for guanine, hypoxanthine and their analogs. PNP deficiency is a rare autosomal recessive genetic disease associated with a severe defect in T-lymphocyte function and neurologic disorder in children, comprising four percent of combined immunodeficiency cases. |
| Concentration | 1.0 mg/ml (determined by Bradford assay) |
| General Readings | Dautant A., et al. (2010) J Biol Chem. 285(38):29502-10. Balakrishnan K., et al. (2010) Blood. 116(6):886-92. |
| Storage | Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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