TGFBR1 / ALK-5 (158-179) - AP22679PU-N

Product Description for TGFBR1 / ALK-5

Rabbit anti Human TGFBR1 / ALK-5.
Properties: (158-179)
Presentation: Purified
Product is tested for Paraffin Sections.

Product Category	Primary Antibodies
Quantity	50 µg
Synonyms	ALK5, Activin receptor-like kinase 5, SKR4, Serine/threonine-protein kinase receptor R4, TGF-beta receptor type-1, TGF-beta type I receptor, TGFR-1, TbetaR-I, Transforming growth factor-beta receptor type I
Presentation	Purified
Reactivity	Hu
Applications	P
Clonality	Polyclonal
Host	Rabbit
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Polyclonal Antibodies (de)

Immunogen	Swiss Prot Num: P36897 Immunogen: TGFBR1 antibody was raised against synthetic peptide corresponding to aa 158-179 of human TGF beta R1 GeneID: 7046
Property	158-179
Application	Immunohistochemistry on Paraffin Sections: 15 µg/ml.
Background	TGFBR1, an Activin/TGFb type protein kinase, is a member of the transforming growth factor-beta (TGFb) signal transduction pathway which controls multiple intracellular functions and the development and homeostasis of most organs and tissues. TGFBR1 is recruited into a heteromeric complex and is phosphorylated by ligand-bound transforming growth factor beta receptor type 2 (TGFBR2). Activated TGFBR1 phosphorylates the receptor-regulated signaling proteins Smad2 and Smad3 which translocate to the nucleus to activate transcription. Mutations in, or loss of expression of, TGFBR1 have been identified in a large number of different tumors and in Loeys-Dietz syndrome.
Concentration	0.2 mg/ml
Storage	StorStore the antibody undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.
Format	Purification: Immunoaffinity Chromatography Buffer System: 10mM PBS, 1% BSA buffer pH 7.4 with 0.09% sodium azide. State: Liquid purified Ig fraction Purified
Specificity	Specificity: This antibody reacts to Transforming Growth Factor Beta Receptor Type 1 (TGFBR1). Species: Human.
Gene ID	7046

Catalog No.	Species	Purity	Source
TP319514	TGFBR1 / ALK-5 (transcript variant 1)
	Human	> 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.	HEK293 cells	20 µg / €748.00
				OriGene Technologies, Inc.
H00007046-Q01-10	TGFBR1 / ALK-5
	Human	12.5% SDS-PAGE Stained with Coomassie Blue.	in vitro transl.
				Abnova Taiwan Corp.
H00007046-Q01-25	TGFBR1 / ALK-5
	Human	12.5% SDS-PAGE Stained with Coomassie Blue.	in vitro transl.
				Abnova Taiwan Corp.
P2845	TGFBR1 / ALK-5
	Human
				Abnova Taiwan Corp.
P4783	TGFBR1 / ALK-5
	Human
				Abnova Taiwan Corp.

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