Product Description for VAMP-associated protein B/C (VAPB)
VAMP-associated protein B/C (VAPB).
Presentation: Purified
Presentation: Purified
Properties for VAMP-associated protein B/C (VAPB)
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.5 mg |
| Synonyms | Vesicle-associated membrane protein-associated protein B/C |
| Presentation | Purified |
| Molecular weight | 27.1 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
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| Purity | > 90 % |
| Background | VAPB, also known as vesicle-associated membrane protein (VAMP)-associated protein B, is a type IV transmembrane protein and member of the VAP family of proteins. This protein may play a role in vesicle trafficking. It is found in plasma and intracellular vesicle membranes as a homodimer and heterodimer with VAPA, and interacts with VAMP1 and VAMP2. Defects in VAPB are a cause of amyotrophic lateral sclerosis type 8 and spinal muscular atrophy autosomal dominant Finkel type. |
| Concentration | 1.0 mg/ml (determined by Bradford assay) |
| General Readings | Nishimura AL, et al. (2004), Am J Hum Genet., 75(5):822-31. Hamamoto I., et al. (2005). J Virol., 79(21):13473-82. |
| Storage | Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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