AR09740PU-L VAMP-associated protein B/C (VAPB) (1-222, His-tag)

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0.5 mg / €820.00
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VAMP-associated protein B/C (VAPB)

AR09740PU-L

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  • AR09740PU-L

Product Description for VAMP-associated protein B/C (VAPB)

VAMP-associated protein B/C (VAPB).
Presentation: Purified

Properties for VAMP-associated protein B/C (VAPB)

Product Category Proteins & Growth Factors
Quantity 0.5 mg
Synonyms Vesicle-associated membrane protein-associated protein B/C
Presentation Purified
Molecular weight 27.1 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
O95292
Purity > 90 %
Background VAPB, also known as vesicle-associated membrane protein (VAMP)-associated protein B, is a type IV transmembrane protein and member of the VAP family of proteins. This protein may play a role in vesicle trafficking. It is found in plasma and intracellular vesicle membranes as a homodimer and heterodimer with VAPA, and interacts with VAMP1 and VAMP2. Defects in VAPB are a cause of amyotrophic lateral sclerosis type 8 and spinal muscular atrophy autosomal dominant Finkel type.
Concentration 1.0 mg/ml (determined by Bradford assay)
General Readings Nishimura AL, et al. (2004), Am J Hum Genet., 75(5):822-31.
Hamamoto I., et al. (2005). J Virol., 79(21):13473-82.
Storage Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human VAPB protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MAKVEQVLSL EPQHELKFRG PFTDVVTTNL KLGNPTDRNV CFKVKTTAPR RYCVRPNSGI IDAGASINVS VMLQPFDYDP NEKSKHKFMV QSMFAPTDTS DMEAVWKEAK PEDLMDSKLR CVFELPAEND KPHDVEINKI ISTTASKTET PIVSKSLSSS LDDTEVKKVM EECKRLQGEV QRLREENKQF KEEDGLRMRK TVQSNSPISA LAPTGKEEGL ST
Molecular weight:
(242aa) confirmed by MALDI-TOF (molecular size on SDS-PAGE will appear higher).
Format
Buffer System:
20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Purity:
>90%
State:
Liquid purified protein
Purified
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