Ribonuclease UK114 / HRSP12 (1-137, His-tag) - AR09777PU-L

Product Description for Ribonuclease UK114 / HRSP12

Ribonuclease UK114 / HRSP12.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	0.5 mg
Synonyms	14.5 kDa translational inhibitor protein, PSP, UK114 antigen homolog, p14.5
Presentation	Purified
Molecular weight	16.6 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: P52758
Purity	> 95 %
Background	HRSP12, also called ribonuclease UK114, is an endoribonuclease found predominantly in human adult kidney and liver, and which is responsible for inhibiting translation by cleaving mRNA. This protein cleaves phosphodiester bonds only in single-stranded RNA. It may be an important biomarker for hepatic carcinoma.
Concentration	1.0 mg/ml (determined by BCA assay)
General Readings	Manjasetty BA, et al. (2004). Proteins 54(4):797-800.
Storage	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human HRSP12 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. AA Sequence: `MGSSHHHHHH SSGLVPRGSH MSSLIRRVIS TAKAPGAIGP YSQAVLVDRT IYISGQIGMD PSSGQLVSGG VAEEAKQALK NMGEILKAAG CDFTNVVKTT VLLADINDFN TVNEIYKQYF KSNFPARAAY QVAALPKGSR IEIEAVAIQG PLTTASL` Molecular weight: (157aa), confirmed by MALDI-TOF
Format	Buffer System: 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.1M NaCl, 1mM DTT Purity: >95% State: Liquid purified protein Purified