Product Description for MAPRE1
MAPRE1.
Presentation: Purified
Presentation: Purified
Properties for MAPRE1
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.1 mg |
| Synonyms | APC-binding protein EB1, End-binding protein 1, Microtubule-associated protein RP/EB family member 1 |
| Presentation | Purified |
| Molecular weight | 32.2 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Purity | > 90 % |
| Background | MAPRE1, also known as EB1, belongs to the intermediate/early gene family. This protein first identified by its binding to the APC protein which is often mutated in familial and sporadic forms of colorectal cancer. It localizes to microtubules, especially the growing ends, in interphase cells. During mitosis, the protein is associated with the centrosomes and spindle microtubules. MAPRE1 is involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes. |
| Concentration | 0.5 mg/ml (determined by Bradford assay) |
| General Readings | Zhang T., et al. (2009) J Cell Sci. 122(Pt 9):1401-9. Tirnauer JS., et al. (2002) Mol Biol Cell. 13(10):3614-26. |
| Storage | Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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