Product Description for METTL1
METTL1.
Presentation: Purified
Presentation: Purified
Properties for METTL1
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 50 µg |
| Synonyms | C12orf1, Methyltransferase-like protein 1, tRNA (guanine-N(7)-)-methyltransferase, tRNA(m7G46)-methyltransferas |
| Presentation | Purified |
| Molecular weight | 33.6 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
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|---|---|
| Purity | > 90 % |
| Background | METTL1 is known as tRNA (guanine-N(7)-)-methyltransferase which belongs to the methyltransferase superfamily. METTL1 shows high sequence similarity to yeast ORF YDL201w and has been shown to be inactivated by phosphorylation. This protein contains a conserved S-adenosylmethionine-binding motif and is inactivated by phosphylation. It catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. |
| Concentration | 0.5 mg/ml (determined by Bradford assay) |
| General Readings | Matsumoto K., et al. (2008) J. Biotechnol. 133: 453-460. Alexandrov A., et al. (2002) RNA 8:1253-1266. |
| Storage | Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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