Product Description for TFAM / TCF6
TFAM / TCF6.
Presentation: Purified
Presentation: Purified
Properties for TFAM / TCF6
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 10 µg |
| Synonyms | Mitochondrial transcription factor 1, MtTF1, TCF-6, TCF6L2, Transcription factor 6, Transcription factor 6-like 2, mitochondrial Transcription factor A |
| Presentation | Purified |
| Molecular weight | 26.6 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Purity | > 85 % |
| Background | TFAM, also known as MtTF1 or mtTFA, is a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. TFAM is located primarily in the nuclei of elongated spermatids and may be involved in the regulation of gene expression of the haploid male genome. TFAM has been associated with mitochondrial disorder in humans characterized by ocular myopathy, exercise intolerance and muscle wasting. |
| Concentration | 0.25 mg/ml (determined by Bradford assay) |
| General Readings | Sinha RA., et al. (2010) Biochem Biophys Res Commun. 397(3):548-52. Aquilano K., et al. (2010) J Biol Chem. 285(28):21590-9. |
| Storage | Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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