Product Description for Desmin
Mouse anti Chicken, Human, Mouse, Porcine, Rabbit, Rat Desmin D9.
Presentation: Purified
Product is tested for Frozen Sections, Western blot / Immunoblot, Paraffin Sections.
Presentation: Purified
Product is tested for Frozen Sections, Western blot / Immunoblot, Paraffin Sections.
Properties for Desmin
| Product Category | Primary Antibodies |
|---|---|
| Quantity | 0.1 mg |
| Synonyms | DES |
| Presentation | Purified |
| Reactivity | Chk, Hu, Ms, Por, Rb, Rt |
| Applications | C, P, WB |
| Clonality | Monoclonal |
| Clone | D9 |
| Host | Mouse |
| Isotype | IgG1 |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Monoclonal Antibodies (de) |
Datasheet Extract
| Immunogen |
|
|---|---|
| Isotype control | AM03095PU-N, SM10P (for use in human samples), SM20P (for use in rat samples) |
| Application | Immunoblotting. Immunohistochemistry on Frozen Sections. Immunohistochemistry on Paraffin Embedded Sections. Rrecommended Dilutions: 1/25-1/200 for immunohistochemistry with avidinbiotinylated horseradish peroxidase complex (ABC) as detection reagent) and 1/100–1/1000 for immunoblotting. |
| Background | Desmin (53 kDa) exhibits a high degree of tissue specificity, its expression being predominantly confined to all types of muscle cells (cardiac, skeletal and smooth muscle). Regulation of desmin expression is stage and tissue-specific, since it is induced during terminal development of, for example, skeletal muscle cell differentiation. In skeletal en cardiac muscle cells desmin is localized in the Z-disk region and at the intercalated disk. The expression pattern of desmin in smooth muscle is much more heterogenous. Coexpression of vimentin and desmin has been observed in tumors derived from muscle tissue, i.e. rhabdomyosarcomas and leiomyosarcomas. Furthermore, during myocard dysfunction dramatic changes in the distribution of desmin have been observed. |
| Concentration | 1.0 mg/ml |
| General Readings |
|
| Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| Format |
|
| Species Reactivity |
|
| Specificity |
|
| Gene ID | 1674 |
Accessory Products
Proteins and/or Positive Controls
Proteins for Desmin (7 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| TP720562 |
Desmin |
||||||
|
Human |
> 95 % Preparation: . Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining. |
E. coli |
10 µg /
€299.00
|
|||
| OriGene Technologies, Inc. | |||||||
| TP760253 |
Desmin (full length, N-term HIS tag) |
||||||
|
Human |
> 80 % Preparation: . Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
E. coli |
50 µg /
€205.00
|
|||
| OriGene Technologies, Inc. | |||||||
| AR09361PU-N |
Desmin |
||||||
|
Human | Purified | > 95 % determined by SDS gelelectrophoresis | E. coli |
0.25 mg /
€520.00
|
||
| OriGene Technologies GmbH | |||||||
| AR09361PU-S |
Desmin |
||||||
|
|
Human | Purified | > 95 % determined by SDS gelelectrophoresis | E. coli |
0.1 mg /
€360.00
|
||
| OriGene Technologies GmbH | |||||||
| H00001674-Q01-10 |
Desmin |
||||||
|
|
Human | Purified | 12.5% SDS-PAGE Stained with Coomassie Blue. | ||||
| Abnova Taiwan Corp. | |||||||
| H00001674-Q01-25 |
Desmin |
||||||
|
|
Human | Purified | 12.5% SDS-PAGE Stained with Coomassie Blue. | ||||
| Abnova Taiwan Corp. | |||||||
| P1241 |
Desmin |
||||||
|
|
Human | ||||||
| Abnova Taiwan Corp. | |||||||
Positive controls for Desmin (1 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| NBL1-09840 |
Desmin Lysate |
||||||
![Western Blot: Desmin Lysate [NBL1-09840] - Western Blot experiments.
Left-Control; Right -Over-expression Lysate for DES](https://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/Novus/Desmin%20Lysate-Western%20Blot-NBL1-09840-img0001.jpg) |
|||||||
| Novus Biologicals Inc. | |||||||
Recommended Secondary Antibodies for Desmin (11 products)
| Catalog No. | Host | Clone/Iso. | Pres. | React. | Applications | ||
|---|---|---|---|---|---|---|---|
| R1253AP |
Mouse IgG (H+L chain) antibody |
||||||
|
|
Rabbit | AP | C, E, WB | ||||
| OriGene Technologies GmbH | |||||||
| R1253B |
Mouse IgG (H+L chain) antibody |
||||||
|
|
Rabbit | Biotin | C, E, WB | ||||
| OriGene Technologies GmbH | |||||||
| R1253F |
Mouse IgG (H+L chain) antibody |
||||||
|
|
Rabbit | FITC | E, ICC/IF | ||||
| OriGene Technologies GmbH | |||||||
| R1253HRP |
Mouse IgG (H+L chain) antibody |
||||||
|
Rabbit | HRP | C, E, WB | ||||
| OriGene Technologies GmbH | |||||||
| R1253TR |
Mouse IgG (H+L chain) antibody |
||||||
|
|
Rabbit | Texas Red | ICC/IF | ||||
| OriGene Technologies GmbH | |||||||
| R1403R |
Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody |
||||||
|
|
Rabbit | PE | F | ||||
| OriGene Technologies GmbH | |||||||
| R1405R |
Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody |
||||||
|
|
Goat | PE | |||||
| OriGene Technologies GmbH | |||||||
| R1455R |
Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody |
||||||
|
|
Donkey | PE | |||||
| OriGene Technologies GmbH | |||||||
| R1457C2 |
Mouse IgG (H+L chain), adsorbed antibody |
||||||
|
|
Goat | Cy2 | |||||
| OriGene Technologies GmbH | |||||||
| R1457C3 |
Mouse IgG (H+L chain), adsorbed antibody |
||||||
|
|
Goat | Cy3 | |||||
| OriGene Technologies GmbH | |||||||
| R1457C5 |
Mouse IgG (H+L chain), adsorbed antibody |
||||||
|
|
Goat | Cy5 | |||||
| OriGene Technologies GmbH | |||||||
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