Product Description for STAT3
Mouse anti Canine, Human, Mouse STAT3 9E12.
Properties: pTyr705
Presentation: FITC
Product is tested for Immunocytochemistry/Immunofluorescence.
Properties: pTyr705
Presentation: FITC
Product is tested for Immunocytochemistry/Immunofluorescence.
Properties for STAT3
| Product Category | Primary Antibodies |
|---|---|
| Quantity | 0.1 mg |
| Synonyms | APRF, Acute-phase response factor, STAT-3, Signal transducer and activator of transcription 3 |
| Presentation | FITC |
| Reactivity | Can, Hu, Ms |
| Applications | ICC/IF |
| Clonality | Monoclonal |
| Clone | 9E12 |
| Host | Mouse |
| Isotype | IgG1 |
| Molecular weight | 92 kDa |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Monoclonal Antibodies (de) |
Datasheet Extract
| Immunogen |
|
|---|---|
| Property | pTyr705 |
| Isotype control | SM10F (for use in human samples) |
| Add. information | For Immunoblotting, Immunoprecipitation or ELISA, clone 9E12 is available as purified or Biotin-labelled antibody (Cat.no. AM00148PU-N or AM00148BT-N). |
| Application | Immunocytochemistry: 1-10 µg/ml. |
| Background | The STAT proteins serve as both cytoplasmic signal transducers and nuclear activators of transcription. STATs are mediators involved in cytokine signalling. In response to a specific cytokine signal, STAT proteins are phosphorylated on conserved tyrosine residues. Phosphorylated STAT proteins dimerize via their SH2 domains and move to the nucleus. The STAT dimers bind to specific DNA elements resulting in transcriptional regulation of downstream target genes. STAT3 is activated by tyrosine phosphorylation at residue Tyr 705 in cells treated with interleukin 6 or EGF. Activated STAT3 can bind to DNA either as homodimer or as heterodimer with STAT1. |
| Concentration | 0.5 mg/ml |
| Storage | Aliquote and freeze in liquid nitrogen. Avoid repeated freezing and thawing. The antibody is stable at -80°C for one year. Thaw aliquots at 37°C. Thawed aliquots may be stored at 2-8°C up to 3 months. |
| Format |
|
| Specificity |
|
| Gene ID | 6774 |
Accessory Products
Proteins and/or Positive Controls
Proteins for STAT3 (8 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| TP312394 |
STAT3 (transcript variant 3) |
||||||
|
Human |
> 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
20 µg /
€748.00
|
|||
| OriGene Technologies, Inc. | |||||||
| TP315836 |
STAT3 (transcript variant 1) |
||||||
|
Human |
> 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
20 µg /
€748.00
|
|||
| OriGene Technologies, Inc. | |||||||
| H00006774-P01-10 |
STAT3 |
||||||
|
Human | 12.5% SDS-PAGE Stained with Coomassie Blue. | in vitro transl. | ||||
| Abnova Taiwan Corp. | |||||||
| H00006774-P01-25 |
STAT3 |
||||||
|
|
Human | 12.5% SDS-PAGE Stained with Coomassie Blue. | in vitro transl. | ||||
| Abnova Taiwan Corp. | |||||||
| H00006774-Q01-10 |
STAT3 |
||||||
|
|
Human | in vitro transl. | |||||
| Abnova Taiwan Corp. | |||||||
| H00006774-Q01-25 |
STAT3 |
||||||
|
|
Human | in vitro transl. | |||||
| Abnova Taiwan Corp. | |||||||
| P0543 |
STAT3 |
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|
|
Human | ||||||
| Abnova Taiwan Corp. | |||||||
| P1423 |
STAT3 |
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|
|
Human | ||||||
| Abnova Taiwan Corp. | |||||||
Positive controls for STAT3 (4 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| NBL1-16525 |
STAT3 Lysate |
||||||
![Western Blot: STAT3 Lysate [NBL1-16525] - Western Blot experiments.
Left-Control; Right -Over-expression Lysate for STAT3](https://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/Novus/STAT3%20Lysate-Western%20Blot-NBL1-16525-img0001.jpg) |
|||||||
| Novus Biologicals Inc. | |||||||
| NBL1-16526 |
STAT3 Lysate |
||||||
![Western Blot: STAT3 Lysate [NBL1-16526] - Western Blot experiments.
Left-Control; Right -Over-expression Lysate for STAT3](https://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/Novus/STAT3%20Lysate-Western%20Blot-NBL1-16526-img0001.jpg) |
|||||||
| Novus Biologicals Inc. | |||||||
| LY403728 |
STAT3 overexpression lysate |
||||||
|
0.1 mg /
€495.00
|
||||||
| OriGene Technologies, Inc. | |||||||
| LY408332 |
STAT3 overexpression lysate |
||||||
|
0.1 mg /
€295.00
|
||||||
| OriGene Technologies, Inc. | |||||||
Recommended Secondary Antibodies for STAT3 (11 products)
| Catalog No. | Host | Clone/Iso. | Pres. | React. | Applications | ||
|---|---|---|---|---|---|---|---|
| R1253AP |
Mouse IgG (H+L chain) antibody |
||||||
|
|
Rabbit | AP | C, E, WB | ||||
| OriGene Technologies GmbH | |||||||
| R1253B |
Mouse IgG (H+L chain) antibody |
||||||
|
|
Rabbit | Biotin | C, E, WB | ||||
| OriGene Technologies GmbH | |||||||
| R1253F |
Mouse IgG (H+L chain) antibody |
||||||
|
|
Rabbit | FITC | E, ICC/IF | ||||
| OriGene Technologies GmbH | |||||||
| R1253HRP |
Mouse IgG (H+L chain) antibody |
||||||
|
Rabbit | HRP | C, E, WB | ||||
| OriGene Technologies GmbH | |||||||
| R1253TR |
Mouse IgG (H+L chain) antibody |
||||||
|
|
Rabbit | Texas Red | ICC/IF | ||||
| OriGene Technologies GmbH | |||||||
| R1403R |
Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody |
||||||
|
|
Rabbit | PE | F | ||||
| OriGene Technologies GmbH | |||||||
| R1405R |
Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody |
||||||
|
|
Goat | PE | |||||
| OriGene Technologies GmbH | |||||||
| R1455R |
Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody |
||||||
|
|
Donkey | PE | |||||
| OriGene Technologies GmbH | |||||||
| R1457C2 |
Mouse IgG (H+L chain), adsorbed antibody |
||||||
|
|
Goat | Cy2 | |||||
| OriGene Technologies GmbH | |||||||
| R1457C3 |
Mouse IgG (H+L chain), adsorbed antibody |
||||||
|
|
Goat | Cy3 | |||||
| OriGene Technologies GmbH | |||||||
| R1457C5 |
Mouse IgG (H+L chain), adsorbed antibody |
||||||
|
|
Goat | Cy5 | |||||
| OriGene Technologies GmbH | |||||||
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