4E-BP2 (1-120, His-tag) - AR09904PU-N

Product Description for 4E-BP2

4E-BP2.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	0.1 mg
Synonyms	EIF4EBP2, Eukaryotic translation initiation factor 4E-binding protein 2, eIF4E-binding protein 2
Presentation	Purified
Molecular weight	15.1 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: Q13542
Purity	> 85 %
Background	4E-BP2 (EIF4EBP2) is a member of the eukaryotic translation initiation factor 4E binding protein family. This protein binds eIF4E and inhibits translation initiation. However, insulin and other growth factors can release this inhibition via a phosphorylation-dependent disruption of their binding to eIF4E. It mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase pathway. Regulation of this protein has been implicated in cell proliferation, cell differentiation and viral infection.
Concentration	0.5 mg/ml (determined by Bradford assay)
Storage	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant Human EIF4EBP2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. AA Sequence: `MGSSHHHHHH SSGLVPRGSH MSSSAGSGHQ PSQSRAIPTR TVAISDAAQL PHDYCTTPGG TLFSTTPGGT RIIYDRKFLL DRRNSPMAQT PPCHLPNIPG VTSPGTLIED SKVEVNNLNN LNNHDRKHAV GDDAQFEMDI` Molecular weight: (140aa) confirmed by MALDI-TOF
Format	Buffer System: 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT, 0.1M NaCl Purity: >85% State: Liquid purified protein Purified