ZCCHC17 (1-241, His-tag) - AR09917PU-L

Product Description for ZCCHC17

ZCCHC17.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	0.25 mg
Synonyms	HSPC243, HSPC251, LDC4, Nucleolar protein of 40 kDa, PS1D, Pnn-interacting nucleolar protein, Putative S1 RNA-binding domain protein, Zinc finger CCHC domain-containing protein 17, pNO40
Presentation	Purified
Molecular weight	kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: Q9NP64
Purity	> 90 %
Background	ZCCHC17, also known as pNO40 or PS1D, is a 241 amino acid protein that interacts with both Pinin and the 60S ribosomal subunit. Localizing to nucleolus, ZCCHC17 is ubiquitously expressed and has been suggested to play a role in ribosome maturation and biogenesis.
Concentration	0.25 mg/ml (determined by Bradford assay)
General Readings	Chang W.-L., et al. (2003) Biochem. Biophys. Res. Commun. 307:569-577. Betarbet, R., et al. (2008) Neurobiol. Dis. 31: 309-315.
Storage	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human ZCCHC17 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. AA Sequence: `MGSSHHHHHH SSGLVPRGSH MGSMNSGRPE TMENLPALYT IFQGEVAMVT DYGAFIKIPG CRKQGLVHRT HMSSCRVDKP SEIVDVGDKV WVKLIGREMK NDRIKVSLSM KVVNQGTGKD LDPNNVIIEQ EERRRRSFQD YTGQKITLEA VLNTTCKKCG CKGHFAKDCF MQPGGTKYSL IPDEEEEKEE AKSAEFEKPD PTRNPSRKRK KEKKKKKHRD RKSSDSDSSD SESDTGKRAR HTSKDSKAAK KKKKKKKHKK KHKE` Molecular weight: (264aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher).
Format	Buffer System: 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 20% glycerol, 0.1M NaCl, 0.1mM PMSF Purity: >90% State: Liquid purified protein Purified