AR09922PU-N CMPK1 (1-228, His-tag)

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0.1 mg / €400.00
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CMPK1

AR09922PU-N

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  • AR09922PU-N

Product Description for CMPK1

CMPK1.
Presentation: Purified

Properties for CMPK1

Product Category Proteins & Growth Factors
Quantity 0.1 mg
Synonyms CMK, CMPK, Cytidine monophosphate kinase, Cytidylate kinase, Deoxycytidylate kinase, UCK, UMK, UMP-CMP kinase, UMP/CMP kinase, UMP/CMPK, UMPK, Uridine monophosphate kinase, Uridine monophosphate/cytidine monophosphate kinase
Presentation Purified
Molecular weight kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P30085
Purity > 90 %
Background CMPK1, also known as UMP-CMP kinase and deoxycytidylate kinase, is an enzyme that catalyzes the phosphoryl transfer from ATP to UMP, CMP and dCMP. This enzymatic reaction leads to the formation of ADP and the corresponding nucleoside diphosphate, which are required for cellular nucleic acid synthesis. It also plays an important role in the activation of pyrimidine analogs, which are clinically useful anti-cancer and anti-viral drugs.
Concentration 1.0 mg/ml (determined by Bradford assay)
General Readings Van Rompay A.R., et al. (2000), Pharmacol. Ther.. 87: 189-198.
Liou J.Y., et al. (2002). Cancer Res. 62: 1624-1631.
Storage Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human CMPK1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MLSRCRSGLL HVLGLSFLLQ TRRPILLCSP RLMKPLVVFV LGGPGAGKGT QCARIVEKYG YTHLSAGELL RDERKNPDSQ YGELIEKYIK EGKIVPVEIT ISLLKREMDQ TMAANAQKNK FLIDGFPRNQ DNLQGWNKTM DGKADVSFVL FFDCNNEICI ERCLERGKSS GRSDDNRESL EKRIQTYLQS TKPIIDLYEE MGKVKKIDAS KSVDEVFDEV VQIFDKEG
Molecular weight:
(248aa), confirmed by MALDI-TOF
Format
Buffer System:
20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 1mM DTT, 100mM NaCl
Purity:
>90%
State:
Liquid purified protein
Purified
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