Product Description for CLEC4A
Mouse anti Human CLEC4A 111F8.04.
Presentation: Purified
Product is tested for Immunoprecipitation, Frozen Sections, Western blot / Immunoblot, Flow Cytometry.
Presentation: Purified
Product is tested for Immunoprecipitation, Frozen Sections, Western blot / Immunoblot, Flow Cytometry.
Properties for CLEC4A
| Product Category | Primary Antibodies |
|---|---|
| Quantity | 50 µg |
| Synonyms | C-type lectin DDB27, C-type lectin domain family 4 member A, C-type lectin superfamily member 6, CLECSF6, DCIR, Dendritic cell immunoreceptor, HDCGC13P, LLIR, Lectin-like immunoreceptor |
| Presentation | Purified |
| Reactivity | Hu |
| Applications | C, F, IP, WB |
| Clonality | Monoclonal |
| Clone | 111F8.04 |
| Host | Mouse |
| Isotype | IgG1 |
| Shipping to | Germany, USA/Canada |
| PDF datasheet | View Datasheet |
| Manufacturer | Dendritics SAS |
Datasheet Extract
| Immunogen |
|
|---|---|
| Isotype control | AM03095PU-N, SM10P (for use in human samples) |
| Application | DDX0180P-50 / DDX0180P-100 Purified: FACS surface, ImmunoHistoChemistry frozen sections, Western Blot, Immunoprecipitation. DDX0180A488-50 / DDX0180A488-100 Alexa-fluor®488: FACS surface, ImmunoFluorescence, ImmunoHistoChemistry frozen sections, Western Blot. DDX0180A546-50 / DDX0180A546-100 Alexa-fluor®546: ImmunoFluorescence, Western Blot. DDX0180A647-50 / DDX0180A647-100 Alexa-fluor®647: FACS surface, Western Blot. DDX0180B-50 / DDX0180B-100 Biotin: ImmunoHistoChemistry frozen sections, Western Blot. *This monoclonal antibody may be used between 5-20 μg/ml. |
| Background | DCIR (dendritic cell immunoreceptor), also known as LLIR, DDB27, CLECSF6, HDCGC13P, is a member of the Dectin-2 family of C-type lectins. DCIR is expressed as a type II membrane glycoprotein of 237 aa with a single carbohydrate recognition domain (CRD), closest in homology to those of the macrophage lectin and hepatic asialoglycoprotein receptors. In contrast to the other members of this family, the intracellular domain of DCIR contains a consensus immunoreceptor tyrosine-based inhibitory motif (ITIM). DCIR is expressed on dendritic cells, monocytes, macrophages, B lymphocytes, neutrophils, granulocytes and plasmacytoid dendritic cells, but not detected on NK and T cells. In vitro, DCIR is strongly expressed by DCs derived from blood monocytes cultured with GM-CSF and IL-4 with a higher expression in CD14+ than CD1a+ derived DC. Finally, DCIR expression is down-regulated by signals inducing DC maturation such as CD40 ligand, LPS, or TNF-. Thus, DCIR is differentially expressed on DCs depending on their origin and stage of maturation/activation. DCIR represents a novel surface molecule expressed by antigenpresenting cells, and of potential importance in regulation of DC function. (Bates EE et al, 1999; J. Immunol., 163: 1973-1983). |
| Product Citations |
|
| Storage | -20°C. KEEP CONTENTS STERILE: no preservative. Purified antibodies: avoid repeated freeze/thaw cycles. Coupled antibodies: glycerol protects from freezing. |
| Format |
|
| Specificity |
|
| Gene ID | 50856 |
Accessory Products
Proteins and/or Positive Controls
Proteins for CLEC4A (2 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| H00050856-P01-10 |
CLEC4A |
||||||
|
Human | Purified | 12.5% SDS-PAGE Stained with Coomassie Blue. | ||||
| Abnova Taiwan Corp. | |||||||
| H00050856-P01-25 |
CLEC4A |
||||||
|
|
Human | Purified | 12.5% SDS-PAGE Stained with Coomassie Blue. | ||||
| Abnova Taiwan Corp. | |||||||
Positive controls for CLEC4A (4 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| H00050856-T01 |
CLEC4A 293T Cell Transient Overexpression Lysate(Denatured) |
||||||
|
|||||||
| Abnova Taiwan Corp. | |||||||
| LY402515 |
CLEC4A overexpression lysate |
||||||
|
0.1 mg /
€295.00
|
||||||
| OriGene Technologies, Inc. | |||||||
| LY405133 |
CLEC4A overexpression lysate |
||||||
|
0.1 mg /
€295.00
|
||||||
| OriGene Technologies, Inc. | |||||||
| LY430687 |
CLEC4A overexpression lysate |
||||||
|
0.1 mg /
€315.00
|
||||||
| OriGene Technologies, Inc. | |||||||
Recommended Secondary Antibodies for CLEC4A (11 products)
| Catalog No. | Host | Clone/Iso. | Pres. | React. | Applications | ||
|---|---|---|---|---|---|---|---|
| R1253AP |
Mouse IgG (H+L chain) antibody |
||||||
|
|
Rabbit | AP | C, E, WB | ||||
| OriGene Technologies GmbH | |||||||
| R1253B |
Mouse IgG (H+L chain) antibody |
||||||
|
|
Rabbit | Biotin | C, E, WB | ||||
| OriGene Technologies GmbH | |||||||
| R1253F |
Mouse IgG (H+L chain) antibody |
||||||
|
|
Rabbit | FITC | E, ICC/IF | ||||
| OriGene Technologies GmbH | |||||||
| R1253HRP |
Mouse IgG (H+L chain) antibody |
||||||
|
Rabbit | HRP | C, E, WB | ||||
| OriGene Technologies GmbH | |||||||
| R1253TR |
Mouse IgG (H+L chain) antibody |
||||||
|
|
Rabbit | Texas Red | ICC/IF | ||||
| OriGene Technologies GmbH | |||||||
| R1403R |
Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody |
||||||
|
|
Rabbit | PE | F | ||||
| OriGene Technologies GmbH | |||||||
| R1405R |
Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody |
||||||
|
|
Goat | PE | |||||
| OriGene Technologies GmbH | |||||||
| R1455R |
Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody |
||||||
|
|
Donkey | PE | |||||
| OriGene Technologies GmbH | |||||||
| R1457C2 |
Mouse IgG (H+L chain), adsorbed antibody |
||||||
|
|
Goat | Cy2 | |||||
| OriGene Technologies GmbH | |||||||
| R1457C3 |
Mouse IgG (H+L chain), adsorbed antibody |
||||||
|
|
Goat | Cy3 | |||||
| OriGene Technologies GmbH | |||||||
| R1457C5 |
Mouse IgG (H+L chain), adsorbed antibody |
||||||
|
|
Goat | Cy5 | |||||
| OriGene Technologies GmbH | |||||||
Compare Products
You have no items to compare.
My Cart
You have no items in your shopping cart.
