Product Description for Interleukin-17A (IL17A)
Mouse anti Human Interleukin-17A (IL17A) 412H6.03.
Presentation: Purified
Product is tested for Flow Cytometry.
Presentation: Purified
Product is tested for Flow Cytometry.
Properties for Interleukin-17A (IL17A)
| Product Category | Primary Antibodies |
|---|---|
| Quantity | 50 µg |
| Synonyms | CTLA-8, CTLA8, Cytotoxic T-lymphocyte-associated antigen 8, IL-17, IL-17A, IL17 |
| Presentation | Purified |
| Reactivity | Hu |
| Applications | F |
| Clonality | Monoclonal |
| Clone | 412H6.03 |
| Host | Mouse |
| Isotype | IgG1 |
| Shipping to | Germany, USA/Canada |
| PDF datasheet | View Datasheet |
| Manufacturer | Dendritics SAS |
Datasheet Extract
| Immunogen |
|
|---|---|
| Isotype control | AM03095PU-N, SM10P (for use in human samples) |
| Application | DDX0339P-50 DDX0339P-100 Purified: FACS intracellular. Usage recommendation: *This monoclonal antibody may be used between 1-10 μg/ml. *Optimal dilution should be determined by each laboratory for each application. *Coupled antibody: to maintain RT before use. |
| Background | IL-17 (cytotoxic T lymphocyte associated antigen 8) is a CD4+ T cell-derived cytokine that stimulates stromal cells and macrophages to secrete proinflammatory cytokines. To address a possible mechanism by which IL-17 may promote alloreactivity, we examined the influence of IL-17 on the differentiation and function of bone marrow-derived cells propagated in GM-CSF with or without IL-4 to promote dendritic cell (DC) growth. A minor proportion of CD11c+ DC expressed the IL-17R. IL-17 promoted the maturation of DC progenitors, as evidenced by increased cell surface expression of CD11c, costimulatory molecules (CD40, CD80, CD86), and MHC class II Ag, and allostimulatory capacity. IL-17 had a lesser effect on the phenotype and function of more fully differentiated myeloid DC. These findings suggest a role for IL-17 in allogeneic T cell proliferation that may be mediated in part via a maturation-inducing effect on DC. IL-17 appears to be a novel target for therapeutic intervention in allograft rejection. hIL17 stimulate epithelial, endothelial, and fibroblastic cells to secrete cytokines such as IL-6, IL-8, and G-CSF and PGE2. (Fossiez F et al, 1996 ; J. Exp. Med., 183:2593-2603 ; Fossiez F. et al, 1998 ; Int. Rev. Immunol., 16:541-551). |
| Concentration | 0.5 mg/ml |
| Product Citations |
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| General Readings | |
| Storage | -20°C. KEEP CONTENTS STERILE: no preservative. Purified antibodies: avoid repeated freeze/thaw cycles. Coupled antibodies: glycerol protects from freezing. |
| Format |
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| Specificity |
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| Gene ID | 3605 |
Accessory Products
Proteins and/or Positive Controls
Proteins for Interleukin-17A (IL17A) (17 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| TP318057 |
Interleukin-17A (IL17A) |
||||||
|
Human |
> 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
20 µg /
€748.00
|
|||
| OriGene Technologies, Inc. | |||||||
| TP720016 |
Interleukin-17A (IL17A) |
||||||
|
Human |
> 95 % Preparation: . Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining. |
E. coli |
10 µg /
€299.00
|
|||
| OriGene Technologies, Inc. | |||||||
| TP723199 |
Interleukin-17A (IL17A) |
||||||
|
Human |
> 95 % Preparation: . Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining. |
E. coli |
25 µg /
€230.00
|
|||
| OriGene Technologies, Inc. | |||||||
| TP723711 |
Interleukin-17A (IL17A) |
||||||
|
Human |
> 98 % Preparation: . Purity Detail: Purity is >98%, as determined by Coomassie stained SDS-PAGE. |
E. coli |
10 µg /
€195.00
|
|||
| OriGene Technologies, Inc. | |||||||
| TP723780 |
Interleukin-17A (IL17A) |
||||||
|
Human |
> 98 % Preparation: . Purity Detail: >98%, as determined by Coomassie stained SDS-PAGE. |
E. coli |
10 µg /
€355.00
|
|||
| OriGene Technologies, Inc. | |||||||
| AR51903PU-N |
Interleukin-17A (IL17A) (24-155, His-tag) |
||||||
|
Human | Purified | > 90 % by SDS - PAGE |
0.25 mg /
€1,070.00
|
|||
| OriGene Technologies GmbH | |||||||
| AR51903PU-S |
Interleukin-17A (IL17A) (24-155, His-tag) |
||||||
|
|
Human | Purified | > 90 % by SDS - PAGE |
50 µg /
€320.00
|
|||
| OriGene Technologies GmbH | |||||||
| PA090 |
Interleukin-17A (IL17A) |
||||||
|
|
Human | Purified | ≥ 98 pure by SDS-PAGE and HPLC analyses. | E. coli | |||
| OriGene Technologies GmbH | |||||||
| PA090X |
Interleukin-17A (IL17A) |
||||||
|
|
Human | Purified | ≥ 98 pure by SDS-PAGE and HPLC analyses. | E. coli | |||
| OriGene Technologies GmbH | |||||||
| H00003605-Q01-10 |
Interleukin-17A (IL17A) |
||||||
|
|
Human | Purified | 12.5% SDS-PAGE Stained with Coomassie Blue. | ||||
| Abnova Taiwan Corp. | |||||||
| H00003605-Q01-25 |
Interleukin-17A (IL17A) |
||||||
|
|
Human | Purified | 12.5% SDS-PAGE Stained with Coomassie Blue. | ||||
| Abnova Taiwan Corp. | |||||||
| P3523 |
Interleukin-17A (IL17A) |
||||||
|
|
Human | ||||||
| Abnova Taiwan Corp. | |||||||
| P3631 |
Interleukin-17A (IL17A) |
||||||
|
|
Human | ||||||
| Abnova Taiwan Corp. | |||||||
| P3814 |
Interleukin-17A (IL17A) |
||||||
|
|
Human | ||||||
| Abnova Taiwan Corp. | |||||||
| P4579 |
Interleukin-17A (IL17A) |
||||||
|
|
Human | ||||||
| Abnova Taiwan Corp. | |||||||
| P4799 |
Interleukin-17A (IL17A) |
||||||
|
|
Human | ||||||
| Abnova Taiwan Corp. | |||||||
| NBP1-46090 |
Interleukin-17A (IL17A) |
||||||
|
|
Human | Purified | |||||
| Novus Biologicals Inc. | |||||||
Positive controls for Interleukin-17A (IL17A) (2 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| LY400795 |
IL17A overexpression lysate |
||||||
|
0.1 mg /
€295.00
|
||||||
| OriGene Technologies, Inc. | |||||||
| NBL1-11912 |
IL17 Lysate |
||||||
![Western Blot: IL17 Lysate [NBL1-11912] - Western Blot experiments.
Left-Control; Right -Over-expression Lysate for IL17A](https://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/Novus/IL17%20Lysate-Western%20Blot-NBL1-11912-img0001.jpg) |
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| Novus Biologicals Inc. | |||||||
Recommended Secondary Antibodies for Interleukin-17A (IL17A) (11 products)
| Catalog No. | Host | Clone/Iso. | Pres. | React. | Applications | ||
|---|---|---|---|---|---|---|---|
| R1253AP |
Mouse IgG (H+L chain) antibody |
||||||
|
|
Rabbit | AP | C, E, WB | ||||
| OriGene Technologies GmbH | |||||||
| R1253B |
Mouse IgG (H+L chain) antibody |
||||||
|
|
Rabbit | Biotin | C, E, WB | ||||
| OriGene Technologies GmbH | |||||||
| R1253F |
Mouse IgG (H+L chain) antibody |
||||||
|
|
Rabbit | FITC | E, ICC/IF | ||||
| OriGene Technologies GmbH | |||||||
| R1253HRP |
Mouse IgG (H+L chain) antibody |
||||||
|
Rabbit | HRP | C, E, WB | ||||
| OriGene Technologies GmbH | |||||||
| R1253TR |
Mouse IgG (H+L chain) antibody |
||||||
|
|
Rabbit | Texas Red | ICC/IF | ||||
| OriGene Technologies GmbH | |||||||
| R1403R |
Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody |
||||||
|
|
Rabbit | PE | F | ||||
| OriGene Technologies GmbH | |||||||
| R1405R |
Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody |
||||||
|
|
Goat | PE | |||||
| OriGene Technologies GmbH | |||||||
| R1455R |
Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody |
||||||
|
|
Donkey | PE | |||||
| OriGene Technologies GmbH | |||||||
| R1457C2 |
Mouse IgG (H+L chain), adsorbed antibody |
||||||
|
|
Goat | Cy2 | |||||
| OriGene Technologies GmbH | |||||||
| R1457C3 |
Mouse IgG (H+L chain), adsorbed antibody |
||||||
|
|
Goat | Cy3 | |||||
| OriGene Technologies GmbH | |||||||
| R1457C5 |
Mouse IgG (H+L chain), adsorbed antibody |
||||||
|
|
Goat | Cy5 | |||||
| OriGene Technologies GmbH | |||||||
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