RBM8A / RBM8 (1-174, His-tag) - AR09930PU-L

Product Description for RBM8A / RBM8

RBM8A / RBM8.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	0.25 mg
Synonyms	BOV-1, Binder of OVCA1-1, HSPC114, MDS014, RNA-binding motif protein 8A, RNA-binding protein 8A, RNA-binding protein Y14, Ribonucleoprotein RBM8A, Y14
Presentation	Purified
Molecular weight	20.9 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: Q9Y5S9
Purity	> 90 %
Background	RBM8A is a member of the EJC (The exon junction complex) that is involved in mRNA export, cytoplasmic localization and nonsense mediated mRNA decay. This protein has the ability to communicate to the cytoplasm the processing history of the mRNA, including the position of the removed introns. Although it shuttles to the cytoplasm, it is predominantly detected in the nucleus and is colocalized with oskar mRNA at the posterior pole of the cell.
Concentration	0.5 mg/ml (determined by Bradford assay)
General Readings	Reichert V.L. et al. (2002) Genes Dev., 16: 2778-2791. Dostie J. et al. (2002) Curr. Biol. 12: 1060-1067.
Storage	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human RBM8A protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography. AA Sequence: `MADVLDLHEA GGEDFAMDED GDESIHKLKE KAKKRKGRGF GSEEGSRARM REDYDSVEQD GDEPGPQRSV EGWILFVTGV HEEATEEDIH DKFAEYGEIK NIHLNLDRRT GYLKGYTLVE YETYKEAQAA MEGLNGQDLM GQPISVDWCF VRGPPKGKRR GGRRRSRSPD RRRRLEHHHH HH` Molecular weight: (182aa), confirmed by MALDI-TOF
Format	Buffer System: 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.1M NaCl, 1mM DTT Purity: >90% State: Liquid purified protein Purified