AM26081PU-N HIV-1 Nef Protein antibody

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0.1 mg / €420.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

Mouse anti Human HIV-1 N5 (01-011)

AM26081PU-N

Product Description for HIV-1

Mouse anti Human HIV-1 N5 (01-011).
Properties: Nef Protein
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Western blot / Immunoblot.

Properties for HIV-1

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms HIV-I, HIV1, Human immunodeficiency virus type 1
Presentation Aff - Purified
Reactivity Hu
Applications E, WB
Clonality Monoclonal
Clone N5 (01-011)
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Property Nef Protein
Application Titer using rNef protein with subtype A aa. consensus:
ELISA: 1:5000.
Western blot: 1:500.
Background HIV is a highly variable virus which mutates very readily. This means there are many different strains of HIV, even within the body of a single infected person. The strains of HIV1 can be classified into three groups: the "major" group M, the "outlier" group O and the "new" group N. These three groups may represent three separate introductions of simian immunodeficiency virus into humans. Group O appears to be restricted to West-Central Africa and group N, discovered in 1998 in Cameroon, is extremely rare. More than 90% of HIV1 infections belong to HIV1 group M.
Concentration 1.0 mg/ml
General Readings
  1. Collings A, Pitkänen J, Strengell M, Tähtinen M, Lagerstedt A, Hakkarainen K, et al. Humoral and cellular immune responses to HIV-1 nef in mice DNA-immunised with non-replicating or self-replicating expression vectors. Vaccine. 1999 Oct 14;18(5-6):460-7. PubMed PMID: 10519935.
  2. Kjerrström A, Hinkula J, Engström G, Ovod V, Krohn K, Benthin R, et al. Interactions of single and combined human immunodeficiency virus type 1 (HIV-1) DNA vaccines. Virology. 2001 May 25;284(1):46-61. PubMed PMID: 11352667.
Storage Upon receipt, store (in aliquots) at -20 to -70 °C. Avoid repeated freezing and thawing.
Shelf life: One year from despatch.
Format
Purification:
Affinity chromatography
Buffer System:
PBS pH 7.4, with 0.09% sodium azide
State:
Liquid Ig fraction
Aff - Purified
Specificity
Specificity:
This antibody detects HIV-1 rNef (aa 62-68).
It recognizes the Nef of HIV-1 subtypes A, B and C.

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