Osteocrin / OSTN (28-133, His-tag) - AR09945PU-N

Product Description for Osteocrin / OSTN

Osteocrin / OSTN.
Presentation: Purified

Immunogen	Swiss Prot Num: P61366
Purity	> 95 %
Background	Osteocrin (OSTN), also known as Musclin, contains two conserved sequence motifs homologous to the natriuretic peptide family. This protein appears to modulate osteoblastic differentiation and highly expressed in cells of osteoblast lineage and in skeletal muscle tissue. It could also function as an autocrine and paracrine factor linked to glucose metabolism in skeletal muscle.
Concentration	0.5 mg/ml (determined by BCA assay)
General Readings	Thomas G., et al. (2003) J. Biol. Chem. 278: 50563-50571. Bord S., et al. (2005) J Histochem Cytochem. 53(10):1181-7.
Storage	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human OSTN protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. AA Sequence: `MGSSHHHHHH SSGLVPRGSH MVDVTTTEAF DSGVIDVQST PTVREEKSAT DLTAKLLLLD ELVSLENDVI ETKKKRSFSG FGSPLDRLSA GSVDHKGKQR KVVDHPKRRF GIPMDRIGRN RLSNSRG` Molecular weight: (127aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher).
Format	Buffer System: 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 20% glycerol, 200mM NaCl Purity: >95% State: Liquid purified protein Purified