MIP1 alpha / CCL3 (24-92, His-tag) - AR09959PU-L

Product Description for MIP1 alpha / CCL3

MIP1 alpha / CCL3.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	0.25 mg
Synonyms	C-C motif chemokine 3, CCL-3, G0/G1 switch regulatory protein 19-1, G0S19-1 protein, LD78 alpha, MIP-1-alpha, MIP1A, Macrophage Inflammatory Protein 1 alpha, SCYA3, Small-inducible cytokine A3, Tonsillar lymphocyte LD78 alpha protein
Presentation	Purified
Molecular weight	kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: P10147
Purity	> 90 %
Background	Macrophage inflammatory protein-1alpha (MIP1 alpha, CCL3) is a cytokine belonging to the CC chemokine family that is involved in the acute inflammatory state in the recruitment and activation of polymorphonuclear leukocytes. This protein has been identified as one of the major HIV-SFs produced by CD8+ T cells, along with MIP-1beta and RANTES. It acts as an inhibitor of different strains of HIV-1, HIV-2 and SIV infection in a dose-dependent manner.
General Readings	Guan E, et al. (2001) J Biol Chem. 276:12404–9.
Storage	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human CCL3, fused to His-tag at N-terminus, was expressed in E.coli and purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer. AA Sequence: `MGSSHHHHHH SSGLVPRGSH MSLAADTPTA CCFSYTSRQI PQNFIADYFE TSSQCSKPGV IFLTKRSRQV CADPSEEWVQ KYVSDLELSA` Molecular weight: (90aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher).
Format	Buffer System: 10mM Sodium Citrate (pH 3.5) containing 10% glycerol Endotoxin level: < 1.0 EU per 1 μg of protein (determined by LAL method) Purity: >90% State: Liquid purified peptide Purified