NUDT10 / APS2 / DIPP3A (1-164, His-tag) - AR09969PU-N

Product Description for NUDT10 / APS2 / DIPP3A

NUDT10 / APS2 / DIPP3A.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	0.1 mg
Synonyms	5'''-P1, DIPP-3-alpha, DIPP3-alpha, Diadenosine 5', Diphosphoinositol polyphosphate phosphohydrolase 3-alpha, Nucleoside diphosphate-linked moiety X motif 10, P6-hexaphosphate hydrolase 3-alpha, hDIPP3alpha
Presentation	Purified
Molecular weight	19.5 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: Q8NFP7
Purity	> 95 %
Background	NUDT10, also known as APS2 or DIPP3α, is a member of the Nudix hydrolase family of pyrophosphatases. Nudix hydrolases contain a characteristic Nudix domain and are responsible for catalyzing the hydrolysis of nucleoside diphosphate derivatives. It functions as a manganese-dependent polyphosphate phosphohydrolase with an optimum pH of 8.5. This protein specifically metabolizes diadendosine-polyphosphates and, to a lesser extent, diphosphoinositol polyphosphates.
Concentration	0.5 mg/ml (determined by Bradford assay)
General Readings	Hidaka K. et al. (2002) J. Biol. Chem. 277: 32730-32738. Hua L.V. et al. (2003) Biochem. J. 373: 81-89.
Storage	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human NUDT10 protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography. AA Sequence: `MKCKPNQTRT YDPEGFKKRA ACLCFRSERE DEVLLVSSSR YPDRWIVPGG GMEPEEEPGG AAVREVYEEA GVKGKLGRLL GVFEQNQDPK HRTYVYVLTV TELLEDWEDS VSIGRKREWF KVEDAIKVLQ CHKPVHAEYL EKLKLGGSPT NGNSMAPSSP DSDPLEHHHH HH` Molecular weight: (172aa) confirmed by MALDI-TOF
Format	Buffer System: 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT Purity: >95% State: Liquid purified protein Purified