AR09989PU-N TNFSF15 (72-251, His-tag)

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0.1 mg / €320.00
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TNFSF15

AR09989PU-N

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  • AR09989PU-N

Product Description for TNFSF15

TNFSF15.
Presentation: Purified

Properties for TNFSF15

Product Category Proteins & Growth Factors
Quantity 0.1 mg
Synonyms TL1, TL1A, TNF ligand-related molecule 1, Tumor necrosis factor ligand superfamily member 15, VEGI, Vascular endothelial cell growth inhibitor
Presentation Purified
Molecular weight 22.7 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
O95150
Purity > 95 %
Background Tumor necrosis factor ligand superfamily member 15, also known TNFSF15, belongs to the TNF superfamily. TNFSF15 is predominantly expressed in endothelial cells and its expression is inducible by TNFα and IL1α. TNFSF15 is an angiogenesis inhibitor of the TNF family and functions in part by directly inhibiting endothelial cell proliferation. TNFSF15 may act as an autocrine factor to induce apoptosis in endothelial cells via activation of multiple signaling pathways, including stress protein kinases and certain caspases.
Concentration 1.0 mg/ml (determined by Bradford assay)
General Readings Migone T S., et al. (2002) Immunity. 16:479.
Storage Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human TNFSF15 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MLKGQEFAPS HQQVYAPLRA DGDKPRAHLT VVRQTPTQHF KNQFPALHWE HELGLAFTKN RMNYTNKFLL IPESGDYFIY SQVTFRGMTS ECSEIRQAGR PNKPDSITVV ITKVTDSYPE PTQLLMGTKS VCEVGSNWFQ PIYLGAMFSL QEGDKLMVNV SDISLVDYTK EDKTFFGAFL L
Molecular weight:
(201aa) confirmed by MALDI-TOF
Format
Buffer System:
20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 50% glycerol, 0.2M NaCl
Endotoxin level:
< 1.0 EU per 1 ug of protein (determined by LAL assay)
Purity:
>95%
State:
Liquid purified protein
Purified
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