Synaptotagmin-1 (136-382, His-tag) - AR39031PU-N

Product Description for Synaptotagmin-1

Synaptotagmin-1.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	50 µg
Synonyms	SVP65, SYT, SYT1, Synaptotagmin I, Synaptotagmin1, SytI, p65
Presentation	Purified
Molecular weight	29.5 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: P21579
Purity	> 85 % pure by SDS-PAGE
Background	Synaptotagmin-1 (SYT1) belongs to the synaptotagmin family contains 2 C2 domains. The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. SYT1 is the master switch responsible for allowing the human brain to release neurotransmitters.
Concentration	0.25 mg/ml (determined by Bradford assay)
General Readings	Han C., et al. (2009) J. Immunol. 182:2986-2996.
Storage	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant Human SYT1 protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. AA Sequence: `MEPKEEEKLG KLQYSLDYDF QNNQLLVGII QAAELPALDM GGTSDPYVKV FLLPDKKKKF ETKVHRKTLN PVFNEQFTFK VPYSELGGKT LVMAVYDFDR FSKHDIIGEF KVPMNTVDFG HVTEEWRDLQ SAEKEEQEKL GDICFSLRYV PTAGKLTVVI LEAKNLKKMD VGGLSDPYVK IHLMQNGKRL KKKKTTIKKN TLNPYYNESF SFEVPFEQIQ KVQVVVTVLD YDKIGKNDAI GKVFVGYNLE HHHHHH N- terminal Sequence Analysis: Met-Glu-Pro-Lys-Glu` Molecular weight: (256aa), confirmed by MALDI-TOF
Format	Buffer System: 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 20% glycerol, 100mM NaCl Purity: >85% pure by SDS-PAGE State: Liquid purified protein Purified