Product Description for NAT1
NAT1.
Presentation: Purified
Presentation: Purified
Properties for NAT1
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.25 mg |
| Synonyms | AAC, Arylamine N-acetyltransferase 1 |
| Presentation | Purified |
| Molecular weight | 36.1 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
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|---|---|
| Purity | > 85 % |
| Background | NAT1 belongs to the arylamine N-acetyltransferase family. It catalyzes N- or O-acetylation of heterocyclic and arylamine substrates in the detoxification of a wide array of drugs. Certain alleles causing high levels of N-acetyltransferase activity have been associated with colon and urinary bladder cancers, as NAT1 also bioactivate several known carcinogens. This enzyme helps metabolize drugs and other xenobiotics, and participates in the detoxification of a plethora of hydrazine and arylamine drugs. |
| Concentration | 0.5 mg/ml (determined by Bradford assay) |
| General Readings | Gu J., et al. (2005) Multat Res. 581(1-2):97-104. Kiss I., et al. (2004) Anticancer Res. 24(6):3965-70. |
| Storage | Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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