CD317 / BST2 (50-161, His-tag) - AR39057PU-N

Product Description for CD317 / BST2

CD317 / BST2.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	50 µg
Synonyms	BST-2, Bone marrow stromal antigen 2, HM1.24 antigen, Tetherin
Presentation	Purified
Molecular weight	14.8 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: Q10589
Purity	> 80 %
Background	BST2, also known as bone marrow stromal antigen 2, is involved in the growth and development of B-cells. BST2 is a human cellular protein which inhibits retrovirus infection by preventing the diffusion of virus particles after budding from infected cells. Initially discovered as an inhibitor to HIV-1 infection in the absence of Vpu, tetherin has also been shown to inhibit the release of other viruses such as the Lassa and Marburg virions. Also, this protein may play a role in B-cell activation in rheumatoid arthritis.
Concentration	0.5 mg/ml (determined by Bradford assay)
General Readings	Van Damme N., et al. (2008) Cell Host Microbe. 3:245-252. Schubert HL., et al. (2010) Proc Natl Acad Sci U S A. 107(42):17951-6.
Storage	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human BST2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. AA Sequence: `MGSSHHHHHH SSGLVPRGSH MSEACRDGLR AVMECRNVTH LLQQELTEAQ KGFQDVEAQA ATCNHTVMAL MASLDAEKAQ GQKKVEELEG EITTLNHKLQ DASAEVERLR RENQVLSVRI ADKKYYPSSQ DSS` Molecular weight: (133aa), confirmed by MALDI-TOF
Format	Purity: >80% State: Liquid purified protein Purified