Product Description for DCPS
DCPS.
Presentation: Purified
Presentation: Purified
Properties for DCPS
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.25 mg |
| Synonyms | DCS-1, DCS1, HINT-5, HINT5, HSL1, HSPC015, Hint-related 7meGMP-directed hydrolase, Histidine triad protein member 5, Scavenger mRNA-decapping enzyme DcpS |
| Presentation | Purified |
| Molecular weight | 40.8 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Purity | > 90 % |
| Background | DCPS, also known as scavenger mRNA-decapping enzyme, is belongs to the HIT family. It is necessary for the complete degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. A scavenger decapping enzyme, DcpS was shown to hydrolyze the residual m7GpppN cap structure after the complete 3′–5′ degradation of the mRNA by the exosome. DcpS releases m7GMP and is unable to cleave cap structures attached to a long RNA chain. |
| Concentration | 0.5 mg/ml (determined by Bradford assay) |
| General Readings | Liu H., et al. (2002) EMBO J. 21:4699-4708. Kwasnicka D.A., et al. (2003) J. Biol. Chem. 278:39051-39058. |
| Storage | Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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