BM5011 Adeno-Associated Virus 2 / AAV2 (Replicase Rep 78, 52) antibody

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0.1 mg / €380.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

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Mouse anti Adeno-Associated Virus 2 / AAV2 76.3

BM5011

Product Description for Adeno-Associated Virus 2 / AAV2

Mouse anti Adeno-Associated Virus 2 / AAV2 76.3.
Properties: (Replicase Rep 78, 52)
Presentation: Purified
Product is tested for Immunocytochemistry/Immunofluorescence, Immunoprecipitation.

Properties for Adeno-Associated Virus 2 / AAV2

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms AAV-2
Presentation Purified
Applications ICC/IF, IP
Clonality Monoclonal
Clone 76.3
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Immunogen:
Recombinant AAV-2 Rep78 protein, N-terminally truncated by 171 aa
Property Replicase Rep 78, 52
Isotype control AM03095PU-N
Application Immunofluorescence Microscopy: 1/10.
Immunoprecipitation.
Background Adeno-associated virus (AAV) is a small virus which infects humans and some other primate species. AAV is not currently known to cause disease and consequently the virus causes a very mild immune response. AAV can infect both dividing and non-dividing cells and may incorporate its genome into that of the host cell. These features make AAV a very attractive candidate for creating viral vectors for gene therapy, and for the creation of isogenic human disease models. Serotype 2 (AAV2) has been the most extensively examined so far. AAV2 presents natural tropism towards skeletal muscles, neurons, vascular smooth muscle cells and hepatocytes.
General Readings
  1. Wistuba A, Weger S, Kern A, Kleinschmidt JA. Intermediates of adeno-associated virus type 2 assembly: identification of soluble complexes containing Rep and Cap proteins. J Virol. 1995 Sep;69(9):5311-9. PubMed PMID: 7636974. (Free PMC Article available)
  2. Wistuba A, Kern A, Weger S, Grimm D, Kleinschmidt JA. Subcellular compartmentalization of adeno-associated virus type 2 assembly. J Virol. 1997 Feb;71(2):1341-52. PubMed PMID: 8995658. (Free PMC Article available)
Storage Store lyophilized at 2-8°C for 6 months or at -20°C long term.
After reconstitution store the antibody undiluted at 2-8°C for one month
or (in aliquots) at -20°C long term.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Protein A Affinity Chromatography
Buffer System:
Final solution contains PBS, pH 7.4 with 0.09% Sodium Azide as preservative and 0.5% BSA as stabilizer
State:
Lyophilized purified Ig fraction
Purified
Reconstitution:
Restore with 1.0 ml distilled water.
Specificity
Specificity:
Four Replicase proteins (Rep78, Rep68, Rep52 and Rep40) are expressed in different concentrations during infection. Antibody clone 76.3 reacts with Rep proteins (Rep78 and Rep52) of Human AAV-2-infected cells.
It does not react with Rep68 and Rep40.

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