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EUD4501 Substance P antibody

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50 µl / €380.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

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Quick Overview

Guinea Pig anti Fish, Human, Rabbit, Rat Substance P

EUD4501

Product Description for Substance P

Guinea Pig anti Fish, Human, Rabbit, Rat Substance P.
Presentation: Serum
Product is tested for Frozen Sections, Flow Cytometry.

Properties for Substance P

Product Category Primary Antibodies
Quantity 50 µl
Synonyms Substance-P
Presentation Serum
Reactivity Fi, Hu, Rb, Rt
Applications C, F
Clonality Polyclonal
Host Guinea Pig
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P20366
Immunogen:
Substance P conjugated to BSA
GeneID:
6863
Application Immunofluorescence: 1/400-1/800 with overnight incubation at 2-8°C.
Immunohistochemistry on Frozen Sections.
Positive Control: Frozen sections of rat colon.
Background Substance P occurs in nerve fibers of the central and peripheral nervous system and in endocrine cells of the gut. It stimulates smooth muscle contraction, gives rise to vasodilation and is involved in sensory functions. Substance P-containing tumors arising in the ileum are often associated with the carcinoid syndrome, characterized by flushing of the skin, diarrhea, bronchoconstriction and sudden drops in blood pressure. Substance P is commonly found in the midgut carcinoids and some of the symptoms may be related to this peptide.
General Readings
  1. Hardebo JE, Suzuki N, Owman C. Origins of substance P- and calcitonin gene-related peptide-containing nerves in the internal carotid artery of rat. Neurosci Lett. 1989 Jun 5;101(1):39-45. PubMed PMID: 2475826.
  2. Witt M et al. Innervation of developing human taste buds. An immunihistochemical study. Histochem. Cell Bio 109 (3), 281-291 (1998)
  3. Shahbazi F, Karila P, Olsson C, Holmgren S, Conlon JM, Jensen J. Primary structure, distribution, and effects on motility of CGRP in the intestine of the cod Gadus morhua. Am J Physiol. 1998 Jul;275(1 Pt 2):R19-28. PubMed PMID: 9688955.
  4. Gölfert F, Witt M, Scheele K, Hofer A, Kasper M, Funk RH. Hints of a functional connection between the neuropeptidergic innervation of arteriovenous anastomoses and the appearance of epithelioid cells in the rabbit ear. Histochem J. 1998 Jun;30(6):435-45. PubMed PMID: 10192543.
  5. Kressel M, Radespiel-Tröger M. Anterograde tracing and immunohistochemical characterization of potentially mechanosensitive vagal afferents in the esophagus. J Comp Neurol. 1999 Sep 13;412(1):161-72. PubMed PMID: 10440717.
Storage Prior to reconstitution store the antibody (undiluted) at 2-8°C.
Following reconstitution store (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
State:
Lyophilized serum
Serum
Reconstitution:
Dissolve the antiserum in 50-100 µl distilled water, and dilute further in 0.1 M PBS with 1% BSA and 0.09% NaN3.
Specificity
Specificity:
This antibody reacts to Substance P.
Absorption with 10-100 µg SP and NKA per ml diluted antiserum abolishes the staining while GRP and NKB do not.
Species:
Human, Rat, Rabbit, and Fish (Cod).
Gene ID 6863

Accessory Products

Proteins and/or Positive Controls

Proteins for Substance P (5 products)

Catalog No. Species Pres. Purity   Source  

Protachykinin-1 (TAC1) (20-129, His-tag)
Protachykinin-1 (TAC1) Human Purified > 95 % by SDS - PAGE E. coli
0.5 mg / €820.00
  OriGene Technologies GmbH

Protachykinin-1 (TAC1) (20-129, His-tag)
Protachykinin-1 (TAC1) Human Purified > 95 % by SDS - PAGE E. coli
0.1 mg / €320.00
  OriGene Technologies GmbH

Protachykinin-1 (TAC1)
Protachykinin-1 (TAC1) Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

Protachykinin-1 (TAC1)
Protachykinin-1 (TAC1) Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

Protachykinin-1 (TAC1)
Protachykinin-1 (TAC1) Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

Positive controls for Substance P (5 products)

Catalog No. Species Pres. Purity   Source  

Substance P Lysate
Western Blot: Substance P Lysate [NBL1-16667] - Western Blot experiments. Left-Control; Right -Over-expression Lysate for TAC1
  Novus Biologicals Inc.

Substance P Lysate
Western Blot: Substance P Lysate [NBL1-16668] - Western Blot experiments. Left-Control; Right -Over-expression Lysate for TAC1
  Novus Biologicals Inc.

TAC1 293T Cell Transient Overexpression Lysate(Denatured)
TAC1 293T Cell Transient Overexpression Lysate(Denatured)
  Abnova Taiwan Corp.

TAC1 overexpression lysate
TAC1 overexpression lysate
0.1 mg / €295.00
  OriGene Technologies, Inc.

TAC1 overexpression lysate
TAC1 overexpression lysate
  OriGene Technologies, Inc.

Recommended Secondary Antibodies for Substance P (8 products)

Catalog No. Host Clone/Iso. Pres.   React. Applications  

Guinea pig IgG (H+L chain) antibody
Guinea pig IgG (H+L chain) antibody Rabbit AP
    OriGene Technologies GmbH

Guinea pig IgG (H+L chain) antibody
Guinea pig IgG (H+L chain) antibody Rabbit FITC
    OriGene Technologies GmbH

Guinea pig IgG (H+L chain) antibody
Guinea pig IgG (H+L chain) antibody Rabbit HRP GP E, P, WB
    OriGene Technologies GmbH

Guinea pig IgG (H+L chain) antibody
Guinea pig IgG (H+L chain) antibody Rabbit Aff - Purified
    OriGene Technologies GmbH

Guinea pig IgG (H+L chain) antibody
Guinea pig IgG (H+L chain) antibody Rabbit TRITC
    OriGene Technologies GmbH

Guinea pig IgG (H+L chain, adsorbed) antibody
Guinea pig IgG (H+L chain, adsorbed) antibody Goat Cy2
    OriGene Technologies GmbH

Guinea pig IgG (H+L chain), adsorbed antibody
Guinea pig IgG (H+L chain), adsorbed antibody Goat Cy3
    OriGene Technologies GmbH

Guinea pig IgG (H+L chain), adsorbed antibody
Guinea pig IgG (H+L chain), adsorbed antibody Goat Cy5
    OriGene Technologies GmbH
Click here to see all secondary antibodies for Substance P
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  • Germany
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