AR39147PU-L Beta-crystallin S (1-178, His-tag)

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0.5 mg / €820.00
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Beta-crystallin S

AR39147PU-L

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  • AR39147PU-L

Product Description for Beta-crystallin S

Beta-crystallin S.
Presentation: Purified

Properties for Beta-crystallin S

Product Category Proteins & Growth Factors
Quantity 0.5 mg
Synonyms CRYGS, GRYG8, Gamma-S-crystallin, Gamma-crystallin S
Presentation Purified
Molecular weight 23.6 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P22914
Purity > 95 %
Background Crystallins are water soluble structural proteins found in the vertebrate eye. Mammalian crystallins are classified in three forms, designated alplha, beta and gamma. Crystallins, as the principal components of the lens, function to increase the refractive index of the eye during accommodation by forming high-molecular weight aggregates which maintain transparency. CRYGS, also known as beta-crystallin S, is exists as a monomer which does not aggregate. This gene encodes the most significant gamma-crystallin in adult eye lens tissue. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation.
Concentration 1.0 mg/ml (determined by BCA assay)
General Readings Sun H., et al. (2005) J Med Genet. 42(9):706-10.
Jester JV., et al. (2008) Semin Cell Dev Biol. 19(2):82-93.
Storage Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human CRYGS protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MGSHMSKTGT KITFYEDKNF QGRRYDCDCD CADFHTYLSR CNSIKVEGGT WAVYERPNFA GYMYILPQGE YPEYQRWMGL NDRLSSCRAV HLPSGGQYKI QIFEKGDFSG QMYETTEDCP SIMEQFHMRE IHSCKVLEGV WIFYELPNYR GRQYLLDKKE YRKPIDWGAA SPAVQSFRRI VE
Molecular weight:
(202aa), confirmed by MALDI-TOF
Format
Buffer System:
20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol,
1mM DTT, 0.1M NaCl
Purity:
>95%
State:
Liquid purified protein
Purified
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