Product Description for MYL6B
MYL6B.
Presentation: Purified
Presentation: Purified
Properties for MYL6B
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.1 mg |
| Synonyms | MLC1SA, Myosin light chain 1 slow-twitch muscle A isoform, Myosin light chain 6B, Smooth muscle and nonmuscle myosin light chain alkali 6B |
| Presentation | Purified |
| Molecular weight | 25.2 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
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| Purity | > 95 % |
| Background | MYL6B is a heavy chain regulator found in smooth muscle and non-muscle Myosin complexes. Contractile activity in smooth muscle is regulated by the calcium/calmodulin-dependent phosphorylation of Myosin light chain by Myosin light chain kinase. MYL6B does not bind calcium during contraction. It is primarily found in a hexamer consisting of four light chains and two heavy chains. It most commonly interacts with Myosin Va, an Actin based motor that can move in large steps. MYL6B is expressed in most tissues with neurons and smooth muscle tissue having the highest expression. |
| Concentration | 1.0 mg/ml (determined by Bradford assay) |
| General Readings | Takeya K., et al. (2008) Am J Physiol Renal Physiol. 294(6):1487-92. |
| Storage | Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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