Product Description for Collagen type I
Collagen type I.
Properties for Collagen type I
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.5 mg |
| Synonyms | Alpha-1 type I collagen, Alpha-2 type I collagen, COL1A1, COL1A2 |
| Species (Protein) | Mouse |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
|
|---|---|
| Purity | > 90 % pure by SDS PAGE. Cross linked collagen type I dimers and trimers represent approximately 10%. |
| Add. information | Impurities: Mouse Collagen type III 10% Mouse collagen (other types) < 1% Non-collagenous proteins < 0.5%. |
| Application | ELISA. |
| Background | Collagens are highly conserved throughout evolution and are characterised by an uninterrupted "Glycine X Y" triplet repeat that is a necessary part of the triple helical structure. Type I collagen (95 kDa) is found in bone, cornea, skin and tendon. Mutations in the encoding gene are associated with osteogenesis imperfecta, Ehlers Danlos syndrome, and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for Platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. |
| Concentration | 1.0 mg/ml |
| General Readings |
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| Storage | Store the antigen undiluted at -20°C only. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| Source | Native from Mouse Tail Tendon. |
| Description |
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| Format |
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