Product Description for Collagen type I
Collagen type I.
Properties for Collagen type I
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 10 mg |
| Synonyms | Alpha-1 type I collagen, Alpha-2 type I collagen, COL1A1, COL1A2 |
| Source | Tail |
| Species (Protein) | Rat |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
|
|---|---|
| Purity | > 90 % pure by SDS-PAGE. Preparation: Collagen was extracted from washed dissected tissue into dilute acetic acid after pepsin treatment. Purification: Differential Salt Precipitation. Rat Collagen type III 10% Rat collagen (other types) < 1% Non-collagen proteins < 0.5% |
| Application | ELISA. |
| Background | Collagens are highly conserved throughout evolution and are characterised by an uninterrupted "Glycine X Y" triplet repeat that is a necessary part of the triple helical structure. Type I collagen (95 kDa) is found in bone, cornea, skin and tendon. Mutations in the encoding gene are associated with osteogenesis imperfecta, Ehlers Danlos syndrome, and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for Platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. |
| General Readings |
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| Storage | Store at -20°C only. DO NOT FREEZE after reconstitution. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| Source | (Rat tail tendon) |
| Description |
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| Format |
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