Product Description for Prolactin / PRL
Prolactin / PRL.
Presentation: Purified
Presentation: Purified
Properties for Prolactin / PRL
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.1 mg |
| Presentation | Purified |
| Molecular weight | 23 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
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| Purity | > 95 % by SDS - PAGE |
| Background | Prolactin is a hormone synthesised and secreted by lactotrope cells in the adenohypophysis(anterior pituitary gland). Prolactin has many effects, the most significant of which is to stimulate the mammary glands to produce milk (lactation).Increased serum prolactin during pregnancy causes enlargement of the mammary glands of the breasts and increases the production of milk. Recently, prolactin has demonstrated broader roles in breast cancer development, regulation of reproductive function, and immunoregulation. Prolactin was expressed in E.coli and purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer. |
| Concentration | 1 mg/ml (determined by Bradford assay) |
| General Readings | Ben-jonathan N., et al. (1996) Endocr Rev. 17(6):639-69. Cooke NE., et al. (1981) J. Biol. Chem. 256, 4007-4016. Goffin V., et al. (1999) Mol Cell Endocrinol. 151, 79-87. |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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