Product Description for Thymidine kinase 2 (TK2)
Thymidine kinase 2 (TK2).
Presentation: Purified
Presentation: Purified
Properties for Thymidine kinase 2 (TK2)
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 50 µg |
| Synonyms | TK-2, Thymidine kinase 2 mitochondrial |
| Presentation | Purified |
| Molecular weight | 30.2 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
|
|---|---|
| Purity | > 85 % by SDS - PAGE |
| Background | TK2, also known as thymidine kinase 2 mitochondrial, belongs to the DCK-DGK family. Thymidine kinase is an enzyme, a phosphotransferase (a kinase): 2-deoxythymidine kinase, ATP-thymidine 5-phosphotransferase, It can be found in most living cells. It is present in two forms in mammalian cells, TK1 and TK2. Certain viruses also have genetic information for expression of viral thymidine kinases. Thymidine kinases have a key function in the synthesis of DNA and thereby in cell division, as they are part of the unique reaction chain to introduce deoxythymidine into the DNA. Defects in TK2 are a cause of mitochondrial DNA depletion syndrome type 2 (MTDPS2). A disorder characterized primarily by childhood onset of muscle weakness associated with depletion of mtDNA in skeletal muscle. |
| Concentration | 0.5mg/ml (determined by Bradford assay) |
| General Readings | Saada A., et al. (2001) Nat. Genet. 29:342-344Kit S. (1985). Thymidine kinase. Microbiol. Sci. 2 (12): 369-75. |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| Description |
|
| Format |
|
Compare Products
You have no items to compare.
My Cart
You have no items in your shopping cart.
