Product Description for CXCL1 / GRO-alpha
CXCL1 / GRO-alpha.
Presentation: Purified
Presentation: Purified
Properties for CXCL1 / GRO-alpha
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.5 mg |
| Synonyms | CXCL1, GRO, GRO-alpha(1-73), GRO1, GROA, Growth-regulated alpha protein, MGSA, Melanoma growth stimulatory activity, NAP-3, Neutrophil-activating protein 3, SCYB1 |
| Presentation | Purified |
| Molecular weight | 10.1 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Purity | > 90 % by SDS - PAGE |
| Background | CXCL1/GROa is a growth factor for melanoma cells and a chemotaxin for neutrophils. Similar to other alpha chemokines, this protein is potent neutrophil attractant and activator and is also active toward basophils. In addition, CXCL1 protein may be a therapeutic target as well as a diagnostic marker in ovarian cancer. Recombinant CXCL1 protein was expressed in E.coli and purified by using conventional chromatography techniques |
| Concentration | 1 mg/ml (determined by Bradford assay) |
| General Readings | Kawanishi H, et al. (2008) Clin Cancer Res., 2579-87Yang HT, et al. (2008) Cell Signal, 375-80Yang G, et al. (2006) Proc Natl Acad Sci U S A, 16472-7 |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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